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BCFTools

This is a singularity image to deploy bcftools.

This will produce a Singularity image (suitable for running in a cluster environment) using https://hub.docker.com/r/broadinstitute/picard/. We do this by way of a bootstrap file for the Docker image.

1. Install Singularity

Instructions can be found on the singularity site.

2. Bootstrap the image

sudo singularity create --size 4000 bcftools.img
sudo singularity bootstrap bcftools.img Singularity

3. Run commands

How to access the bcftools runtime executable?

   ./bcftools.img

Program: bcftools (Tools for variant calling and manipulating VCFs and BCFs)
Version: 1.3.1 (using htslib 1.3.1)

Usage:   bcftools [--version|--version-only] [--help] <command> <argument>

Commands:

 -- Indexing
    index        index VCF/BCF files

 -- VCF/BCF manipulation
    annotate     annotate and edit VCF/BCF files
    concat       concatenate VCF/BCF files from the same set of samples
    convert      convert VCF/BCF files to different formats and back
    isec         intersections of VCF/BCF files
    merge        merge VCF/BCF files files from non-overlapping sample sets
    norm         left-align and normalize indels
    plugin       user-defined plugins
    query        transform VCF/BCF into user-defined formats
    reheader     modify VCF/BCF header, change sample names
    view         VCF/BCF conversion, view, subset and filter VCF/BCF files

 -- VCF/BCF analysis
    call         SNP/indel calling
    consensus    create consensus sequence by applying VCF variants
    cnv          HMM CNV calling
    filter       filter VCF/BCF files using fixed thresholds
    gtcheck      check sample concordance, detect sample swaps and contamination
    roh          identify runs of autozygosity (HMM)
    stats        produce VCF/BCF stats

 Most commands accept VCF, bgzipped VCF, and BCF with the file type detected
 automatically even when streaming from a pipe. Indexed VCF and BCF will work
 in all situations. Un-indexed VCF and BCF and streams will work in most but
 not all situations.

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Singularity image for biocontainers samtools

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