Skip to content
Blueprints for a low-cost laser combiner compatible with wide-field and localization microscopy.
Branch: master
Clone or download
Type Name Latest commit message Commit time
Failed to load latest commit information.
Agitation_Module added 3mf MotorHousingV2 file Oct 29, 2019
Electronics added notes on pusling Oct 2, 2019
Laser_Engine Update Sep 26, 2019 added paper reference Oct 16, 2019
laserengine.jpg added private repository Sep 19, 2019
license.txt added private repository Sep 19, 2019
logo.png added private repository Sep 19, 2019

Logo Open-source laser engine

Laser engine

Blueprints for a low-cost laser engine compatible with wide-field and localization microscopy. The laser engine is based on affordable, albeit powerful, laser diodes, a square multimode fiber and a speckle-reduction module.

ℹ️ ​How to navigate the repository

The repository contains the following complementary modules:

  • Agitation module: a box holding a motor suspended by elastic cords for speckle and noise reduction.
  • Laser diode electronics: Electronics to control the power and triggering of the laser diodes from the computer.
  • Laser engine: plans and guidelines of the optical path. It contains several submodules:

⚠️ Safety warning​​s ⚠️

  • Always work with adequate laser light protection.
  • The foam board used in the enclosure is a fire hazard when subjected to strong laser light. Make sure to place beam stops behind the dichroic mirrors and the polarization beam splitter so that no laser beam hits the foam board panels.
  • Building the electronics oneself requires experience in soldering and electronics in general. Make sure you are working safely.

Cite us

D Schroeder*, J Deschamps*, A Dasgupta, U Matti and J Ries, "A cost-efficient open source laser engine for microscopy", bioRxiv 796482; doi:


If you have any question, get in touch with the Ries group.




The electronics was designed by Christian Kieser, Electronics workshop, EMBL.

Pictures credit: EMBL/Marietta Schupp

You can’t perform that action at this time.