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Topological Data Analysis Approach for Single Cell Genomics

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rohitpalsingh/singlecellTDA

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singlecellTDA

g84724

The Focus of the repository is to do the following before performing Downstream Analysis.

Data Pre-Processing

  1. Feature Selection
  2. Dimensionality Reduction
  3. Data Visualization

Down Stream Analysis

  1. Cell Group Annotation
  2. Identifying Infered Trejectories through topomap/mapper/tomato. Identify Major Topological Change during different time course.
  3. Identify key genes driver genes for the differentiation.
  4. Analysising different interesting areas in Single Cell Genomics. Perturbations between treated/condition/simulated and untreated/control/unsimulated samples.

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Topological Data Analysis Approach for Single Cell Genomics

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