CNORfuzzy is an extension to CellNOptR that allows to handle continous values, using constrained fuzzy logic, as described in:

M. K. Morris, J. Saez-Rodriguez, D. Clarke, P. K. Sorger, D. A. Lauffenburger. Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli. PLoS Comp. Biol., 7(3): e1001099, 2011

Please visit the package on the Bioconductor for further details or check http://www.cellnopt.org/ for a detailed description of CellNOptR add-on packages.