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shackett/README.md
  • My professional projects at Calico are primarily in private repos which I hope to open-source in the future. The projects largely fit into two buckets:

    • Development of a robust ecosystem for working with mass spectrometry data combining a configurable Dockerized pipeline and R packages supporting the pipeline and downstream analysis.
    • Approaches using genome-scale systems biology to understand regulation. See Induction Dynamics Expression Atlas and Impulse.
  • My side-projects and past work can be found on my personal website. Here is a brief rundown.

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  1. calico/romic calico/romic Public

    romic represents high-dimensional measurements by persistently tracking features, samples, and measurements as a dataset is modified and reformatted. It provides a suite of functions that build on …

    R 5 1

  2. calico/claman calico/claman Public

    Calico Lipidomics and Metabolomics (CLaM) Analysis provides a suite of functions which support data manipulation, statistical analysis and visualizations of mzrollDB files created by MAVEN.

    R 2

  3. calico/impulse calico/impulse Public

    Fit phenomenological sigmoid and impulse curves with priors to improve interpretability

    R 10 2

  4. simmer simmer Public

    Systematic Identification of Meaningful Metabolic Enzyme Regulation

    R 8 1

  5. mQTL mQTL Public

    Testing how genetic variation in a cross between two parental yeast strains impacts the metabolome

    TeX

  6. dgrtwo/GSEAMA dgrtwo/GSEAMA Public

    Gene Set Enrichment Analysis Made Awesome

    R 10 6