PUMBAA is a MATLAB-based graphical user interface created by Devante Kerr in the Sidorov Lab in the Center for Neuroscience Research at Children's National Hospital. PUMBAA enables phenotyping using a multidimensional behavioral analysis algorithm. Given a rodent behavioral dataset with two genotypes and multiple behaviors, PUMBAA uses multidimensional analysis (principal component analysis + k-means clustering) to predict the genotype of animals based on their behavior.
A complete user guide is available in the .zip file.
If using PUMBAA, please cite Tanas JK, Kerr DD, Wang L, Rai A, Wallaard I, Elgersma Y, and Sidorov MS. Multidimensional analysis of behavior predicts genotype with high accuracy in a mouse model of Angelman syndrome (2022). Translational Psychiatry 12: 426.
PUMBAA v3.1 was updated on 10/5/2022.
PUMBAA v3.3 was updated on 5/7/2024.