Skip to content

MCCS (Molecular Complex Characterization System) example data for scoring and clustering GPCR crystal structures.

Notifications You must be signed in to change notification settings

stcmz/mccs-example-gpcr

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

2 Commits
 
 
 
 
 
 
 
 

Repository files navigation

MCCS Samples

This repository stores the sample data for MCCS (Molecular Complex Characterization System).

1_original_gpcr_pdb_data

This directory include a complete list of GPCR proteins from GPCRdb that have known 3D structures determined by either X-Ray crystallography or cryoEM technique.

All are PDB files included were fetched from https://www.rcsb.org/ directly.

The list snapshot date is June 5, 2019.

2_manually_cleaned_up

We then manually cleaned up the downloaded PDB files keeping only those have a non-peptide binding ligand and put them into this directory.

3_mccs_complete_output

Finally jdock was used to generate the per residue energy contribution, and another script was run for vector clustering and heatmap generation. The entire workspace including input/output/log is provided in this directory.

About

MCCS (Molecular Complex Characterization System) example data for scoring and clustering GPCR crystal structures.

Resources

Stars

Watchers

Forks