REHE: Fast Variance Components Estimation for Linear Mixed Models
Implement estimation of linear mixed model variance components via REHE, with functions written in R.
To use REHE/reREHE for GWAS, use scripts under directory GENESIS_R. Funciton inputs and outputs are made compatible with GENESIS v2.14.3.
To use REHE/reREHE for NetGSA, use implementation available at https://github.com/mikehellstern/netgsa.
For reproducing simulation results and data application results in the manuscript, use scripts under directory Simulation, and data application.
For generating plots used in the manuscript, please refer to files in the directory plots.
For questions of the scripts, please contact Kun Yue at yuek@uw.edu. For questions regarding the content of the manuscript, please contact Ali Shojaie at ashojaie@uw.edu.