About Me

I am a Early Career Group Leader at the Francis Crick Instute, where I head the Dynamics of Living Systems (https://github.com/frohlich-lab). For more information, you can follow me on twitter or read my papers.

Estimation Pipeline

Over the years, I have developed and contributed to several toolboxes that permit the efficient formulation, simulation and calibration of kinetic models of cellular signaling. All toolboxes are modular and interoperable, allowing the flexible definition of customizable analysis pipelines.

• Formulate your model using pysb
• Define your estimation problem using PEtab
• Solve your estimation problem using pyPESTO
• Use the efficient optimizers implemented in fides
• Use the scalable simulate and sensitivity computation methods implemented in AMICI