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SARS-CoV-2 genome sequence data analyses

System requirement

CPU x86-64 (e.g. Intel Core i3/i5/i7 series)
RAM 8 GB or above
OS 64-bit Linux or macOS

Software dependencies

Package name Version Site URL
Perl 5.8 or later https://www.perl.org (Preinstalled in OS)
BEDTools 2.29.2 https://github.com/arq5x/bedtools2
NCBI-BLAST+ 2.2.29 http://ftp.ncbi.nlm.nih.gov/blast/executables/blast+
FATE 2.8.0 https://github.com/Hikoyu/FATE
FAMSA 1.5.12 https://github.com/refresh-bio/FAMSA
ModelTest-NG 0.1.6 https://github.com/ddarriba/modeltest
RAxML-NG 0.9.0 https://github.com/amkozlov/raxml-ng

Preparation before analysis

Above softwares must be installed and in your PATH. Some softwares need to be compiled. (e.g. BEDTools) For Linux users, 'modeltest-ng', including binary distribution, may cause a segmentation fault error when parallel execution is enabled. Consider using 'modeltest-mpi' as 'modeltest-ng' in stead (or set a shell variable 'num_threads' to 1).

Re-analysis

Clone this repository and remove old data before re-analysis. Then, simply execute 'script/all-in-one_analysis.sh' in the top of the repository.

$ git clone https://github.com/Hikoyu/SARS-CoV-2
$ cd SARS-CoV-2
$ rm ref/*.orf.f?a genome/*.fna.* fate/*.bed famsa/*.fna phylogeny/*.* phylogeny/*/DNA/*/*/*.* phylogeny/*/AA/*/*.*
$ ./script/all-in-one_analysis.sh

Now, you can get the multiple sequence alignments of open reading frames, the lists of variable/parsimony-informative sites, and the maximum-likelihood phylogenies. If you want to re-analyze only estimating phylogeny, remove old phylogenetic analysis data and execute 'script/phylogenetic_analysis.sh' in the top of the repository.

$ git clone https://github.com/Hikoyu/SARS-CoV-2
$ cd SARS-CoV-2
$ rm phylogeny/*.* phylogeny/*/DNA/*/*/*.* phylogeny/*/AA/*/*.*
$ ./script/phylogenetic_analysis.sh

Now, you can get the maximum-likelihood phylogenies.

Calculation time

Phylogenetic analyses take a lot of time. They took over 2 weeks in total on my Linux workstation (4C/8T Intel Xeon E3-1240L v3, 16 GB RAM). More CPU cores and/or newer streaming SIMD extensions may contribute to reduce the calculation time. If you intend to just test, reduce the bootstraps replicates to 100 via 'bootstraps_replicates' shell variable in script/phylogenetic_analysis.sh.

Data formats and file extensions

Data format File extension Description
FASTA (DNA) *.fna DNA sequence file
FASTA (AA) *.faa AA sequence file
FASTA index *.fai fasta index file
BED *.bed annotation data file
Newick *.nwk phylogenetic tree file

Files and directories

SARS-CoV-2
├── README.md
├── famsa => including open reading frame sequence data and multiple sequence alignment data
│   ├── SARS-CoV-2_200414.E.aln.fna
│   ├── SARS-CoV-2_200414.E.fna
│   ├── SARS-CoV-2_200414.M.aln.fna
│   ├── SARS-CoV-2_200414.M.fna
│   ├── SARS-CoV-2_200414.N.aln.fna
│   ├── SARS-CoV-2_200414.N.fna
│   ├── SARS-CoV-2_200414.ORF10.aln.fna
│   ├── SARS-CoV-2_200414.ORF10.fna
│   ├── SARS-CoV-2_200414.ORF3a.aln.fna
│   ├── SARS-CoV-2_200414.ORF3a.fna
│   ├── SARS-CoV-2_200414.ORF6.aln.fna
│   ├── SARS-CoV-2_200414.ORF6.fna
│   ├── SARS-CoV-2_200414.ORF7a.aln.fna
│   ├── SARS-CoV-2_200414.ORF7a.fna
│   ├── SARS-CoV-2_200414.ORF8.aln.fna
│   ├── SARS-CoV-2_200414.ORF8.fna
│   ├── SARS-CoV-2_200414.S.aln.fna
│   ├── SARS-CoV-2_200414.S.fna
│   ├── SARS-CoV-2_200414.orf1ab_D.aln.fna
│   ├── SARS-CoV-2_200414.orf1ab_D.fna
│   ├── SARS-CoV-2_200414.orf1ab_U.aln.fna
│   ├── SARS-CoV-2_200414.orf1ab_U.fna
│   ├── msa_list.txt
│   ├── parsimony-informative_site_position_list.txt
│   ├── parsimony-informative_sites.txt
│   ├── variable_site_position_list.txt
│   └── variable_sites.txt
├── fate
│   └── SARS-CoV-2_200414.orf.bed => open reading frame annotation data
├── genome => including SARS-CoV-2 genome sequence data
│   ├── SARS-CoV-2_200414.fna
│   ├── SARS-CoV-2_200414.fna.fai
│   ├── SARS-CoV-2_200414.fna.nhr
│   ├── SARS-CoV-2_200414.fna.nin
│   ├── SARS-CoV-2_200414.fna.nsq
│   └── sample_list.txt
├── phylogeny
│   ├── ModelTest-NG
│   │   ├── AA
│   │   └── DNA
│   │       ├── part
│   │       │   ├── 3rd => including model test data using partitioned model for each ORF and also 1st/2nd and 3rd codon position
│   │       │   │   ├── SARS-CoV-2_200414.ckp
│   │       │   │   ├── SARS-CoV-2_200414.log
│   │       │   │   ├── SARS-CoV-2_200414.out
│   │       │   │   ├── SARS-CoV-2_200414.part.aic
│   │       │   │   ├── SARS-CoV-2_200414.part.aicc
│   │       │   │   ├── SARS-CoV-2_200414.part.bic
│   │       │   │   ├── SARS-CoV-2_200414.part.txt
│   │       │   │   └── SARS-CoV-2_200414.tree
│   │       │   ├── sep => including phylogenetic analysis data using partitioned model for each ORF and also each codon position
│   │       │   │   ├── SARS-CoV-2_200414.ckp
│   │       │   │   ├── SARS-CoV-2_200414.log
│   │       │   │   ├── SARS-CoV-2_200414.out
│   │       │   │   ├── SARS-CoV-2_200414.part.aic
│   │       │   │   ├── SARS-CoV-2_200414.part.aicc
│   │       │   │   ├── SARS-CoV-2_200414.part.bic
│   │       │   │   ├── SARS-CoV-2_200414.part.txt
│   │       │   │   └── SARS-CoV-2_200414.tree
│   │       │   └── uni => including model test data using partitioned model for each ORF
│   │       │       ├── SARS-CoV-2_200414.ckp
│   │       │       ├── SARS-CoV-2_200414.log
│   │       │       ├── SARS-CoV-2_200414.out
│   │       │       ├── SARS-CoV-2_200414.part.aic
│   │       │       ├── SARS-CoV-2_200414.part.aicc
│   │       │       ├── SARS-CoV-2_200414.part.bic
│   │       │       ├── SARS-CoV-2_200414.part.txt
│   │       │       └── SARS-CoV-2_200414.tree
│   │       └── univ
│   │           ├── 3rd => including model test data using partitioned model for each ORF and also 1st/2nd and 3rd codon position
│   │           │   ├── SARS-CoV-2_200414.ckp
│   │           │   ├── SARS-CoV-2_200414.log
│   │           │   ├── SARS-CoV-2_200414.out
│   │           │   ├── SARS-CoV-2_200414.part.aic
│   │           │   ├── SARS-CoV-2_200414.part.aicc
│   │           │   ├── SARS-CoV-2_200414.part.bic
│   │           │   ├── SARS-CoV-2_200414.part.txt
│   │           │   └── SARS-CoV-2_200414.tree
│   │           ├── sep => including model test data using partitioned model for each codon position
│   │           │   ├── SARS-CoV-2_200414.ckp
│   │           │   ├── SARS-CoV-2_200414.log
│   │           │   ├── SARS-CoV-2_200414.out
│   │           │   ├── SARS-CoV-2_200414.part.aic
│   │           │   ├── SARS-CoV-2_200414.part.aicc
│   │           │   ├── SARS-CoV-2_200414.part.bic
│   │           │   ├── SARS-CoV-2_200414.part.txt
│   │           │   └── SARS-CoV-2_200414.tree
│   │           └── uni => including model test data without using partitioned model
│   │               ├── SARS-CoV-2_200414.ckp
│   │               ├── SARS-CoV-2_200414.log
│   │               ├── SARS-CoV-2_200414.out
│   │               └── SARS-CoV-2_200414.tree
│   ├── RAxML-NG
│   │   ├── AA
│   │   └── DNA
│   │       ├── part
│   │       │   ├── 3rd => including phylogenetic analysis data using partitioned model for each ORF and also 1st/2nd and 3rd codon position
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.parse.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.raxml.rba
│   │       │   │   ├── SARS-CoV-2_200414.raxml.reduced.partition
│   │       │   │   ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │       │   │   ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │       │   │   ├── SARS-CoV-2_200414.search.0.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.1.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.10.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.11.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.2.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.3.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.4.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.5.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.6.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.7.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.8.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.9.raxml.log
│   │       │   │   └── SARS-CoV-2_200414.support.raxml.log
│   │       │   ├── sep => including phylogenetic analysis data using partitioned model for each ORF and also each codon position
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.0.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.1.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.10.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.11.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.2.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.3.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.4.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.5.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.6.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.7.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.8.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │       │   │   ├── SARS-CoV-2_200414.9.raxml.startTree
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.parse.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.raxml.bootstraps
│   │       │   │   ├── SARS-CoV-2_200414.raxml.rba
│   │       │   │   ├── SARS-CoV-2_200414.raxml.reduced.partition
│   │       │   │   ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │       │   │   ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │       │   │   ├── SARS-CoV-2_200414.search.0.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.1.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.10.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.11.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.2.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.3.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.4.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.5.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.6.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.7.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.8.raxml.log
│   │       │   │   ├── SARS-CoV-2_200414.search.9.raxml.log
│   │       │   │   └── SARS-CoV-2_200414.support.raxml.log
│   │       │   └── uni => including phylogenetic analysis data using partitioned model for each ORF
│   │       │       ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.0.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.1.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.10.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.11.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.2.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.3.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.4.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.5.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.6.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.7.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.8.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │       │       ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │       │       ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │       │       ├── SARS-CoV-2_200414.9.raxml.startTree
│   │       │       ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │       │       ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │       │       ├── SARS-CoV-2_200414.parse.raxml.log
│   │       │       ├── SARS-CoV-2_200414.raxml.bootstraps
│   │       │       ├── SARS-CoV-2_200414.raxml.rba
│   │       │       ├── SARS-CoV-2_200414.raxml.reduced.partition
│   │       │       ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │       │       ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │       │       ├── SARS-CoV-2_200414.search.0.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.1.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.10.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.11.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.2.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.3.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.4.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.5.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.6.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.7.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.8.raxml.log
│   │       │       ├── SARS-CoV-2_200414.search.9.raxml.log
│   │       │       └── SARS-CoV-2_200414.support.raxml.log
│   │       └── univ
│   │           ├── 3rd => including phylogenetic analysis data using partitioned model for 1st/2nd and 3rd codon position
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.0.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.1.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.10.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.11.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.2.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.3.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.4.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.5.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.6.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.7.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.8.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.9.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │           │   ├── SARS-CoV-2_200414.parse.raxml.log
│   │           │   ├── SARS-CoV-2_200414.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.raxml.rba
│   │           │   ├── SARS-CoV-2_200414.raxml.reduced.partition
│   │           │   ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │           │   ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │           │   ├── SARS-CoV-2_200414.search.0.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.1.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.10.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.11.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.2.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.3.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.4.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.5.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.6.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.7.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.8.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.9.raxml.log
│   │           │   └── SARS-CoV-2_200414.support.raxml.log
│   │           ├── sep => including phylogenetic analysis data using partitioned model for each codon position
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.0.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.1.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.10.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.11.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.2.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.3.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.4.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.5.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.6.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.7.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.8.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │           │   ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │           │   ├── SARS-CoV-2_200414.9.raxml.startTree
│   │           │   ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │           │   ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │           │   ├── SARS-CoV-2_200414.parse.raxml.log
│   │           │   ├── SARS-CoV-2_200414.raxml.bootstraps
│   │           │   ├── SARS-CoV-2_200414.raxml.rba
│   │           │   ├── SARS-CoV-2_200414.raxml.reduced.partition
│   │           │   ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │           │   ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │           │   ├── SARS-CoV-2_200414.search.0.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.1.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.10.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.11.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.2.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.3.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.4.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.5.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.6.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.7.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.8.raxml.log
│   │           │   ├── SARS-CoV-2_200414.search.9.raxml.log
│   │           │   └── SARS-CoV-2_200414.support.raxml.log
│   │           └── uni => including phylogenetic analysis data without using partitioned model
│   │               ├── SARS-CoV-2_200414.0.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.0.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.0.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.0.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.0.raxml.startTree
│   │               ├── SARS-CoV-2_200414.1.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.1.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.1.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.1.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.1.raxml.startTree
│   │               ├── SARS-CoV-2_200414.10.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.10.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.10.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.10.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.10.raxml.startTree
│   │               ├── SARS-CoV-2_200414.11.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.11.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.11.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.11.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.11.raxml.startTree
│   │               ├── SARS-CoV-2_200414.2.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.2.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.2.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.2.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.2.raxml.startTree
│   │               ├── SARS-CoV-2_200414.3.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.3.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.3.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.3.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.3.raxml.startTree
│   │               ├── SARS-CoV-2_200414.4.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.4.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.4.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.4.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.4.raxml.startTree
│   │               ├── SARS-CoV-2_200414.5.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.5.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.5.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.5.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.5.raxml.startTree
│   │               ├── SARS-CoV-2_200414.6.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.6.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.6.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.6.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.6.raxml.startTree
│   │               ├── SARS-CoV-2_200414.7.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.7.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.7.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.7.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.7.raxml.startTree
│   │               ├── SARS-CoV-2_200414.8.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.8.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.8.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.8.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.8.raxml.startTree
│   │               ├── SARS-CoV-2_200414.9.raxml.bestModel
│   │               ├── SARS-CoV-2_200414.9.raxml.bestTree
│   │               ├── SARS-CoV-2_200414.9.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.9.raxml.mlTrees
│   │               ├── SARS-CoV-2_200414.9.raxml.startTree
│   │               ├── SARS-CoV-2_200414.bootstrap.0.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.1.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.10.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.11.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.2.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.3.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.4.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.5.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.6.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.7.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.8.raxml.log
│   │               ├── SARS-CoV-2_200414.bootstrap.9.raxml.log
│   │               ├── SARS-CoV-2_200414.bsconverge.raxml.log
│   │               ├── SARS-CoV-2_200414.parse.raxml.log
│   │               ├── SARS-CoV-2_200414.raxml.bootstraps
│   │               ├── SARS-CoV-2_200414.raxml.rba
│   │               ├── SARS-CoV-2_200414.raxml.reduced.phy
│   │               ├── SARS-CoV-2_200414.raxml.support.nwk => maximum-likelihood phylogeny data with bootstrap values
│   │               ├── SARS-CoV-2_200414.search.0.raxml.log
│   │               ├── SARS-CoV-2_200414.search.1.raxml.log
│   │               ├── SARS-CoV-2_200414.search.10.raxml.log
│   │               ├── SARS-CoV-2_200414.search.11.raxml.log
│   │               ├── SARS-CoV-2_200414.search.2.raxml.log
│   │               ├── SARS-CoV-2_200414.search.3.raxml.log
│   │               ├── SARS-CoV-2_200414.search.4.raxml.log
│   │               ├── SARS-CoV-2_200414.search.5.raxml.log
│   │               ├── SARS-CoV-2_200414.search.6.raxml.log
│   │               ├── SARS-CoV-2_200414.search.7.raxml.log
│   │               ├── SARS-CoV-2_200414.search.8.raxml.log
│   │               ├── SARS-CoV-2_200414.search.9.raxml.log
│   │               └── SARS-CoV-2_200414.support.raxml.log
│   ├── SARS-CoV-2_200414.aln.concat.faa
│   └── SARS-CoV-2_200414.aln.concat.fna
├── ref => including reference open reading frame annotation data
│   ├── MN908947.orf.bed
│   ├── MN908947.orf.faa
│   └── MN908947.orf.fna
└── script
    ├── LICENSE
    ├── all-in-one_analysis.sh
    ├── codon_based_msa.pl
    ├── parallel_phylogeny.pl
    ├── phylogenetic_analysis.sh
    ├── translator.pl
    └── variable_sites_extractor.pl

Meta data of genomes

Accession No. Database name Collection date Country State/City Notes
LC534419 Genbank 09-Mar-2020 Japan Kanagawa
LC534418 Genbank 14-Feb-2020 Japan Kanagawa Diamond Princess cruise ship?
LC528233 Genbank 10-Feb-2020 Japan Kanagawa Diamond Princess cruise ship?
LC528232 Genbank 10-Feb-2020 Japan Kanagawa Diamond Princess cruise ship?
LC529905 Genbank Jan-2020 Japan Tokyo
MT308700 Genbank 12-Mar-2020 USA Michigan
MT308699 Genbank 12-Mar-2020 USA Michigan
MT308698 Genbank 12-Mar-2020 USA Michigan
MT308697 Genbank 11-Mar-2020 USA Michigan
MT308696 Genbank 09-Mar-2020 USA Michigan
MT308695 Genbank 10-Mar-2020 USA Michigan
MT308694 Genbank 11-Mar-2020 USA Michigan
MT308693 Genbank 10-Mar-2020 USA Michigan
MT308692 Genbank 09-Mar-2020 USA Michigan
MT308704 Genbank Apr-2020 USA North Carolina
MT308703 Genbank Apr-2020 USA North Carolina
MT308702 Genbank Apr-2020 USA North Carolina
MT304491 Genbank 01-Mar-2020 USA Texas
MT304490 Genbank 01-Mar-2020 USA Texas
MT304489 Genbank 29-Feb-2020 USA Texas
MT304488 Genbank 01-Mar-2020 USA Rhode Island
MT304487 Genbank 01-Mar-2020 USA Oregon
MT304486 Genbank 02-Mar-2020 USA New York
MT304485 Genbank 02-Mar-2020 USA New Hampshire
MT304484 Genbank 29-Feb-2020 USA New Hampshire
MT304483 Genbank 01-Mar-2020 USA Illinois
MT304482 Genbank 01-Mar-2020 USA Illinois
MT304481 Genbank 04-Mar-2020 USA Georgia
MT304480 Genbank 03-Mar-2020 USA Georgia
MT304479 Genbank 03-Mar-2020 USA Georgia
MT304478 Genbank 02-Mar-2020 USA Florida
MT304477 Genbank 02-Mar-2020 USA Arizona
MT304476 Genbank 29-Feb-2020 South Korea
MT304475 Genbank 29-Feb-2020 South Korea
MT304474 Genbank 27-Feb-2020 South Korea
MT281577 Genbank 10-Mar-2020 China Fuyang
MT292582 Genbank 06-Mar-2020 Spain Valencia
MT292581 Genbank 27-Feb-2020 Spain Valencia
MT292580 Genbank 27-Feb-2020 Spain Valencia
MT292579 Genbank 09-Mar-2020 Spain Valencia
MT292578 Genbank 09-Mar-2020 Spain Valencia
MT292577 Genbank 08-Mar-2020 Spain Valencia
MT292576 Genbank 10-Mar-2020 Spain Valencia
MT292575 Genbank 10-Mar-2020 Spain Valencia
MT292574 Genbank 02-Mar-2020 Spain Valencia
MT292573 Genbank 09-Mar-2020 Spain Valencia
MT292572 Genbank 10-Mar-2020 Spain Valencia
MT292571 Genbank 09-Mar-2020 Spain Valencia
MT292570 Genbank 10-Mar-2020 Spain Valencia
MT292569 Genbank 09-Mar-2020 Spain Valencia
MT276331 Genbank 29-Feb-2020 USA Texas
MT276330 Genbank 28-Feb-2020 USA Florida
MT276329 Genbank 28-Feb-2020 USA Florida
MT276328 Genbank 27-Feb-2020 USA Oregon
MT276327 Genbank 29-Feb-2020 USA Georgia
MT276326 Genbank 29-Feb-2020 USA Georgia
MT276325 Genbank 27-Feb-2020 USA Washington
MT276324 Genbank 26-Feb-2020 USA California
MT276323 Genbank 28-Feb-2020 USA Rhode Island
MT263074 Genbank 10-Mar-2020 Peru
MT256918 Genbank 06-Mar-2020 Spain Valencia
MT256917 Genbank 02-Mar-2020 Spain Valencia
MT198652 Genbank 05-Mar-2020 Spain Valencia
MT233523 Genbank 04-Mar-2020 Spain Valencia
MT233522 Genbank 02-Mar-2020 Spain Valencia
MT233521 Genbank 27-Feb-2020 Spain Valencia
MT233520 Genbank 26-Feb-2020 Spain Valencia
MT233519 Genbank 27-Feb-2020 Spain Valencia
MT226610 Genbank 20-Jan-2020 China
MT198653 Genbank 08-Mar-2020 Spain Valencia
MT198651 Genbank 04-Mar-2020 Spain Valencia
MT163721 Genbank 01-Mar-2020 USA Washington
MT163720 Genbank 01-Mar-2020 USA Washington
MT163719 Genbank 01-Mar-2020 USA Washington
MT163718 Genbank 29-Feb-2020 USA Washington
MT163717 Genbank 28-Feb-2020 USA Washington
MT163716 Genbank 27-Feb-2020 USA Washington
MT126808 Genbank 28-Feb-2020 Brazil Sao Paulo Traveler from Switzerland and Italy (Milan) to Brazil
MT066156 Genbank 30-Jan-2020 Italy
MT295465 Genbank 27-Mar-2020 USA
MT295464 Genbank 10-Mar-2020 USA
MT093571 Genbank 07-Feb-2020 Sweden
MT246667 Genbank 19-Jan-2020 USA Washington
MT233526 Genbank 19-Jan-2020 USA Washington
MT020781 Genbank 29-Jan-2020 Finland Lapland
MT320891 Genbank 09-Mar-2020 Iran
MT320538 Genbank Mar-2020 France
MT300186 Genbank 02-Apr-2020 USA North Carolina
MT281530 Genbank 09-Mar-2020 Iran
MT291836 Genbank 29-Jan-2020 China Beijing
MT291835 Genbank 27-Jan-2020 China Beijing
MT291834 Genbank 28-Jan-2020 China Beijing
MT291833 Genbank 28-Jan-2020 China Beijing
MT291832 Genbank 25-Jan-2020 China Beijing
MT291831 Genbank 24-Jan-2020 China Beijing
MT291830 Genbank 30-Dec-2019 China Wuhan
MT291829 Genbank 30-Dec-2019 China Wuhan
MT291828 Genbank 30-Dec-2019 China Wuhan
MT291827 Genbank 30-Dec-2019 China Wuhan
MT291826 Genbank 30-Dec-2019 China Wuhan
MT293225 Genbank 18-Mar-2020 USA Washington
MT293224 Genbank 18-Mar-2020 USA Washington
MT293223 Genbank 18-Mar-2020 USA Washington
MT293222 Genbank 18-Mar-2020 USA Washington
MT293221 Genbank 18-Mar-2020 USA Washington
MT293220 Genbank 18-Mar-2020 USA Washington
MT293219 Genbank 18-Mar-2020 USA Washington
MT293218 Genbank 18-Mar-2020 USA Washington
MT293217 Genbank 17-Mar-2020 USA Washington
MT293216 Genbank 19-Mar-2020 USA Washington
MT293215 Genbank 19-Mar-2020 USA Washington
MT293214 Genbank 19-Mar-2020 USA Washington
MT293213 Genbank 19-Mar-2020 USA Washington
MT293212 Genbank 19-Mar-2020 USA Washington
MT293211 Genbank 19-Mar-2020 USA Washington
MT293210 Genbank 19-Mar-2020 USA Washington
MT293209 Genbank 19-Mar-2020 USA Washington
MT293208 Genbank 19-Mar-2020 USA Washington
MT293207 Genbank 19-Mar-2020 USA Washington
MT293206 Genbank 19-Mar-2020 USA Washington
MT293205 Genbank 19-Mar-2020 USA Washington
MT293204 Genbank 18-Mar-2020 USA Washington
MT293203 Genbank 18-Mar-2020 USA Washington
MT293202 Genbank 19-Mar-2020 USA Washington
MT293201 Genbank 19-Mar-2020 USA Washington
MT293200 Genbank 19-Mar-2020 USA Washington
MT293199 Genbank 19-Mar-2020 USA Washington
MT293198 Genbank 19-Mar-2020 USA Washington
MT293197 Genbank 19-Mar-2020 USA Washington
MT293196 Genbank 19-Mar-2020 USA Washington
MT293195 Genbank 28-Mar-2020 USA Washington
MT293194 Genbank 18-Mar-2020 USA Washington
MT293193 Genbank 27-Mar-2020 USA Washington
MT293192 Genbank 28-Mar-2020 USA Washington
MT293191 Genbank 17-Mar-2020 USA Washington
MT293190 Genbank 17-Mar-2020 USA Washington
MT293189 Genbank 18-Mar-2020 USA Washington
MT293188 Genbank 28-Mar-2020 USA Washington
MT293187 Genbank 17-Mar-2020 USA Washington
MT293186 Genbank 17-Mar-2020 USA Washington
MT293185 Genbank 28-Mar-2020 USA Washington
MT293184 Genbank 18-Mar-2020 USA Washington
MT293183 Genbank 18-Mar-2020 USA Washington
MT293182 Genbank 18-Mar-2020 USA Washington
MT293181 Genbank 18-Mar-2020 USA Washington
MT293180 Genbank 17-Mar-2020 USA Washington
MT293179 Genbank 17-Mar-2020 USA Washington
MT293178 Genbank 26-Mar-2020 USA Washington
MT293177 Genbank 16-Mar-2020 USA
MT293176 Genbank 17-Mar-2020 USA Washington
MT293175 Genbank 30-Mar-2020 USA Washington
MT293174 Genbank 27-Mar-2020 USA Washington
MT293173 Genbank 30-Mar-2020 USA Washington
MT293172 Genbank 17-Mar-2020 USA Washington
MT293171 Genbank 17-Mar-2020 USA Washington
MT293170 Genbank 18-Mar-2020 USA Washington
MT293169 Genbank 17-Mar-2020 USA Washington
MT293168 Genbank 17-Mar-2020 USA Washington
MT293167 Genbank 17-Mar-2020 USA Washington
MT293166 Genbank 17-Mar-2020 USA Washington
MT293165 Genbank 17-Mar-2020 USA Washington
MT293164 Genbank 17-Mar-2020 USA Washington
MT293163 Genbank 29-Mar-2020 USA Washington
MT293162 Genbank 16-Mar-2020 USA Washington
MT293161 Genbank 16-Mar-2020 USA Washington
MT293160 Genbank 16-Mar-2020 USA Washington
MT293159 Genbank 16-Mar-2020 USA Washington
MT293158 Genbank 16-Mar-2020 USA Washington
MT293157 Genbank 29-Mar-2020 USA Washington
MT293156 Genbank 30-Mar-2020 USA Washington
MT276598 Genbank Mar-2020 Israel
MT276597 Genbank Feb-2020 Israel
MT263469 Genbank 23-Mar-2020 USA Washington
MT263468 Genbank 23-Mar-2020 USA Washington
MT263467 Genbank 23-Mar-2020 USA Washington
MT263466 Genbank 23-Mar-2020 USA Washington
MT263465 Genbank 23-Mar-2020 USA Washington
MT263464 Genbank 23-Mar-2020 USA Washington
MT263463 Genbank 23-Mar-2020 USA Washington
MT263462 Genbank 23-Mar-2020 USA Washington
MT263461 Genbank 22-Mar-2020 USA Washington
MT263460 Genbank 24-Mar-2020 USA Washington
MT263459 Genbank 24-Mar-2020 USA Washington
MT263458 Genbank 23-Mar-2020 USA Washington
MT263457 Genbank 24-Mar-2020 USA Washington
MT263456 Genbank 24-Mar-2020 USA Washington
MT263455 Genbank 24-Mar-2020 USA Washington
MT263454 Genbank 24-Mar-2020 USA Washington
MT263453 Genbank 24-Mar-2020 USA Washington
MT263452 Genbank 24-Mar-2020 USA Washington
MT263451 Genbank 24-Mar-2020 USA Washington
MT263450 Genbank 24-Mar-2020 USA Washington
MT263449 Genbank 24-Mar-2020 USA Washington
MT263448 Genbank 24-Mar-2020 USA Washington
MT263447 Genbank 14-Mar-2020 USA Washington
MT263446 Genbank 24-Mar-2020 USA Washington
MT263445 Genbank 24-Mar-2020 USA Washington
MT263444 Genbank 20-Mar-2020 USA Washington
MT263443 Genbank 24-Mar-2020 USA Washington
MT263442 Genbank 24-Mar-2020 USA Washington
MT263441 Genbank 24-Mar-2020 USA Washington
MT263440 Genbank 24-Mar-2020 USA Washington
MT263439 Genbank 24-Mar-2020 USA Washington
MT263438 Genbank 24-Mar-2020 USA Washington
MT263437 Genbank 24-Mar-2020 USA Washington
MT263436 Genbank 24-Mar-2020 USA Washington
MT263435 Genbank 24-Mar-2020 USA Washington
MT263434 Genbank 24-Mar-2020 USA Washington
MT263433 Genbank 24-Mar-2020 USA Washington
MT263432 Genbank 24-Mar-2020 USA Washington
MT263431 Genbank 24-Mar-2020 USA Washington
MT263430 Genbank 24-Mar-2020 USA Washington
MT263429 Genbank 24-Mar-2020 USA Washington
MT263428 Genbank 24-Mar-2020 USA Washington
MT263427 Genbank 24-Mar-2020 USA Washington
MT263426 Genbank 24-Mar-2020 USA Washington
MT263425 Genbank 24-Mar-2020 USA Washington
MT263424 Genbank 24-Mar-2020 USA Washington
MT263423 Genbank 23-Mar-2020 USA Washington
MT263422 Genbank 24-Mar-2020 USA Washington
MT263421 Genbank 24-Mar-2020 USA Washington
MT263420 Genbank 20-Mar-2020 USA Washington
MT263419 Genbank 20-Mar-2020 USA Washington
MT263418 Genbank 24-Mar-2020 USA Washington
MT263417 Genbank 24-Mar-2020 USA Washington
MT263416 Genbank 21-Mar-2020 USA Washington
MT263415 Genbank 24-Mar-2020 USA Washington
MT263414 Genbank 24-Mar-2020 USA Washington
MT263413 Genbank 24-Mar-2020 USA Washington
MT263412 Genbank 22-Mar-2020 USA Washington
MT263411 Genbank 24-Mar-2020 USA Washington
MT263410 Genbank 24-Mar-2020 USA Washington
MT263409 Genbank 22-Mar-2020 USA Washington
MT263408 Genbank 24-Mar-2020 USA Washington
MT263407 Genbank 22-Mar-2020 USA Washington
MT263406 Genbank 21-Mar-2020 USA Washington
MT263405 Genbank 21-Mar-2020 USA Washington
MT263404 Genbank 24-Mar-2020 USA Washington
MT263403 Genbank 20-Mar-2020 USA Washington
MT263402 Genbank 23-Mar-2020 USA Washington
MT263401 Genbank 23-Mar-2020 USA Washington
MT263400 Genbank 23-Mar-2020 USA Washington
MT263399 Genbank 24-Mar-2020 USA Washington
MT263398 Genbank 24-Mar-2020 USA Washington
MT263397 Genbank 24-Mar-2020 USA Washington
MT263396 Genbank 22-Mar-2020 USA Washington
MT263395 Genbank 24-Mar-2020 USA Washington
MT263394 Genbank 22-Mar-2020 USA Washington
MT263393 Genbank 23-Mar-2020 USA Washington
MT263392 Genbank 24-Mar-2020 USA Washington
MT263391 Genbank 24-Mar-2020 USA Washington
MT263390 Genbank 24-Mar-2020 USA Washington
MT263389 Genbank 23-Mar-2020 USA Washington
MT263388 Genbank 23-Mar-2020 USA Washington
MT263387 Genbank 23-Mar-2020 USA Washington
MT263386 Genbank 22-Mar-2020 USA Washington
MT263385 Genbank 23-Mar-2020 USA Washington
MT263384 Genbank 23-Mar-2020 USA Washington
MT263383 Genbank 24-Mar-2020 USA Washington
MT263382 Genbank 23-Mar-2020 USA Washington
MT263381 Genbank 23-Mar-2020 USA Washington
MT262916 Genbank 13-Mar-2020 USA Washington
MT262915 Genbank 13-Mar-2020 USA Washington
MT262914 Genbank 13-Mar-2020 USA Washington
MT262913 Genbank 13-Mar-2020 USA Washington
MT262912 Genbank 13-Mar-2020 USA Washington
MT262911 Genbank 13-Mar-2020 USA Washington
MT262910 Genbank 13-Mar-2020 USA Washington
MT262909 Genbank 13-Mar-2020 USA Washington
MT262908 Genbank 13-Mar-2020 USA Washington
MT262907 Genbank 13-Mar-2020 USA Washington
MT262906 Genbank 13-Mar-2020 USA Washington
MT262905 Genbank 13-Mar-2020 USA Washington
MT262904 Genbank 13-Mar-2020 USA Washington
MT262903 Genbank 13-Mar-2020 USA Washington
MT262902 Genbank 13-Mar-2020 USA Washington
MT262901 Genbank 13-Mar-2020 USA Washington
MT262900 Genbank 13-Mar-2020 USA Washington
MT262899 Genbank 13-Mar-2020 USA Washington
MT262898 Genbank 13-Mar-2020 USA Washington
MT262897 Genbank 13-Mar-2020 USA Washington
MT262896 Genbank 13-Mar-2020 USA Washington
MT262993 Genbank 12-Mar-2020 Pakistan Khyber Pakhtunkhwa
MT259287 Genbank 15-Mar-2020 USA Washington
MT259286 Genbank 15-Mar-2020 USA Washington
MT259285 Genbank 15-Mar-2020 USA Washington
MT259284 Genbank 15-Mar-2020 USA Washington
MT259283 Genbank 15-Mar-2020 USA Washington
MT259282 Genbank 15-Mar-2020 USA Washington
MT259281 Genbank 15-Mar-2020 USA Washington
MT259280 Genbank 15-Mar-2020 USA Washington
MT259279 Genbank 15-Mar-2020 USA Washington
MT259278 Genbank 15-Mar-2020 USA Washington
MT259277 Genbank 15-Mar-2020 USA Washington
MT259276 Genbank 15-Mar-2020 USA Washington
MT259275 Genbank 14-Mar-2020 USA Washington
MT259274 Genbank 14-Mar-2020 USA Washington
MT259273 Genbank 15-Mar-2020 USA Washington
MT259272 Genbank 13-Mar-2020 USA Washington
MT259271 Genbank 15-Mar-2020 USA Washington
MT259270 Genbank 16-Mar-2020 USA Washington
MT259269 Genbank 14-Mar-2020 USA Washington
MT259268 Genbank 13-Mar-2020 USA Washington
MT259267 Genbank 14-Mar-2020 USA Washington
MT259266 Genbank 13-Mar-2020 USA Washington
MT259265 Genbank 13-Mar-2020 USA Washington
MT259264 Genbank 13-Mar-2020 USA Washington
MT259263 Genbank 13-Mar-2020 USA Washington
MT259262 Genbank 14-Mar-2020 USA Washington
MT259261 Genbank 16-Mar-2020 USA Washington
MT259260 Genbank 16-Mar-2020 USA Washington
MT259259 Genbank 16-Mar-2020 USA Washington
MT259258 Genbank 13-Mar-2020 USA Washington
MT259257 Genbank 16-Mar-2020 USA Washington
MT259256 Genbank 13-Mar-2020 USA Washington
MT259255 Genbank 16-Mar-2020 USA Washington
MT259254 Genbank 16-Mar-2020 USA Washington
MT259253 Genbank 16-Mar-2020 USA Washington
MT259252 Genbank 14-Mar-2020 USA Washington
MT259251 Genbank 14-Mar-2020 USA Washington
MT259250 Genbank 14-Mar-2020 USA Washington
MT259249 Genbank 13-Mar-2020 USA Washington
MT259248 Genbank 14-Mar-2020 USA Washington
MT259247 Genbank 16-Mar-2020 USA Washington
MT259246 Genbank 13-Mar-2020 USA Washington
MT259245 Genbank 15-Mar-2020 USA Washington
MT259244 Genbank 16-Mar-2020 USA Washington
MT259243 Genbank 13-Mar-2020 USA Washington
MT259242 Genbank 14-Mar-2020 USA Washington
MT259241 Genbank 16-Mar-2020 USA Washington
MT259240 Genbank 16-Mar-2020 USA Washington
MT259239 Genbank 16-Mar-2020 USA Washington
MT259238 Genbank 16-Mar-2020 USA Washington
MT259237 Genbank 16-Mar-2020 USA Washington
MT259236 Genbank 16-Mar-2020 USA Washington
MT259235 Genbank 13-Mar-2020 USA Washington
MT258383 Genbank 18-Mar-2020 USA California
MT258382 Genbank 18-Mar-2020 USA California
MT258381 Genbank 18-Mar-2020 USA California
MT258380 Genbank 18-Mar-2020 USA California
MT258379 Genbank 18-Mar-2020 USA California
MT258378 Genbank 18-Mar-2020 USA California
MT258377 Genbank 18-Mar-2020 USA California
MT256924 Genbank 11-Mar-2020 Colombia Antioquia
MT259231 Genbank 25-Jan-2020 China Wuhan
MT259230 Genbank 25-Jan-2020 China Wuhan
MT259229 Genbank 26-Jan-2020 China Wuhan
MT259228 Genbank 26-Jan-2020 China Wuhan
MT259227 Genbank 26-Jan-2020 China Wuhan
MT259226 Genbank 10-Jan-2020 China Wuhan
MT253710 Genbank 21-Jan-2020 China Hangzhou
MT253709 Genbank 21-Jan-2020 China Hangzhou
MT253708 Genbank 21-Jan-2020 China Hangzhou
MT253707 Genbank 25-Jan-2020 China Hangzhou
MT253706 Genbank 22-Jan-2020 China Hangzhou
MT253705 Genbank 22-Jan-2020 China Hangzhou
MT253704 Genbank 25-Jan-2020 China Hangzhou
MT253703 Genbank 25-Jan-2020 China Hangzhou
MT253702 Genbank 21-Jan-2020 China Hangzhou
MT253701 Genbank 21-Jan-2020 China Hangzhou
MT253700 Genbank 25-Jan-2020 China Hangzhou
MT253699 Genbank 24-Jan-2020 China Hangzhou
MT253698 Genbank 23-Jan-2020 China Hangzhou
MT253697 Genbank 23-Jan-2020 China Hangzhou
MT253696 Genbank 23-Jan-2020 China Hangzhou
MT251980 Genbank 13-Mar-2020 USA Washington
MT251979 Genbank 14-Mar-2020 USA Washington
MT251978 Genbank 14-Mar-2020 USA Washington
MT251977 Genbank 14-Mar-2020 USA Washington
MT251976 Genbank 14-Mar-2020 USA Washington
MT251975 Genbank 14-Mar-2020 USA Washington
MT251974 Genbank 12-Mar-2020 USA Washington
MT251973 Genbank 14-Mar-2020 USA Washington
MT251972 Genbank 14-Mar-2020 USA Washington
MT246490 Genbank 15-Mar-2020 USA Washington
MT246489 Genbank 14-Mar-2020 USA Washington
MT246488 Genbank 14-Mar-2020 USA Washington
MT246487 Genbank 15-Mar-2020 USA Washington
MT246486 Genbank 14-Mar-2020 USA Washington
MT246485 Genbank 15-Mar-2020 USA Washington
MT246484 Genbank 15-Mar-2020 USA Washington
MT246483 Genbank 15-Mar-2020 USA Washington
MT246482 Genbank 15-Mar-2020 USA Washington
MT246481 Genbank 13-Mar-2020 USA Washington
MT246480 Genbank 13-Mar-2020 USA Washington
MT246479 Genbank 13-Mar-2020 USA Washington
MT246478 Genbank 14-Mar-2020 USA Washington
MT246477 Genbank 14-Mar-2020 USA Washington
MT246476 Genbank 13-Mar-2020 USA Washington
MT246475 Genbank 13-Mar-2020 USA Washington
MT246474 Genbank 14-Mar-2020 USA Washington
MT246473 Genbank 14-Mar-2020 USA Washington
MT246472 Genbank 12-Mar-2020 USA Washington
MT246471 Genbank 14-Mar-2020 USA Washington
MT246470 Genbank 13-Mar-2020 USA Washington
MT246469 Genbank 14-Mar-2020 USA Washington
MT246468 Genbank 14-Mar-2020 USA Washington
MT246467 Genbank 14-Mar-2020 USA Washington
MT246466 Genbank 13-Mar-2020 USA Washington
MT246465 Genbank 13-Mar-2020 USA Washington
MT246464 Genbank 13-Mar-2020 USA Washington
MT246463 Genbank 13-Mar-2020 USA Washington
MT246462 Genbank 13-Mar-2020 USA Washington
MT246461 Genbank 13-Mar-2020 USA Washington
MT246460 Genbank 12-Mar-2020 USA Washington
MT246459 Genbank 12-Mar-2020 USA Washington
MT246458 Genbank 12-Mar-2020 USA Washington
MT246457 Genbank 12-Mar-2020 USA Washington
MT246456 Genbank 13-Mar-2020 USA Washington
MT246455 Genbank 12-Mar-2020 USA Washington
MT246454 Genbank 12-Mar-2020 USA Washington
MT246453 Genbank 13-Mar-2020 USA Washington
MT246452 Genbank 13-Mar-2020 USA Washington
MT246451 Genbank 13-Mar-2020 USA Washington
MT246450 Genbank 13-Mar-2020 USA Washington
MT246449 Genbank 13-Mar-2020 USA Washington
MT240479 Genbank 04-Mar-2020 Pakistan Gilgit
MT192773 Genbank 22-Jan-2020 Viet Nam Ho Chi Minh
MT192772 Genbank 22-Jan-2020 Viet Nam Ho Chi Minh
MT192765 Genbank 11-Mar-2020 USA California
MT192759 Genbank 25-Jan-2020 Taiwan
MT123293 Genbank 29-Jan-2020 China Guangzhou
MT123292 Genbank 27-Jan-2020 China Guangzhou
MT123291 Genbank 29-Jan-2020 China Guangzhou
MT093631 Genbank 08-Jan-2020 China Wuhan
MT121215 Genbank 02-Feb-2020 China Shanghai
MT152824 Genbank 24-Feb-2020 USA Washington
MT135044 Genbank 28-Jan-2020 China Beijing
MT135043 Genbank 28-Jan-2020 China Beijing
MT135042 Genbank 28-Jan-2020 China Beijing
MT135041 Genbank 26-Jan-2020 China Beijing
MT123290 Genbank 05-Feb-2020 China Guangzhou
MT072688 Genbank 13-Jan-2020 Nepal Kathmandu
MT066176 Genbank 05-Feb-2020 Taiwan Taipei
MT066175 Genbank 31-Jan-2020 Taiwan Taipei
MT050493 Genbank 31-Jan-2020 India Kerala
MT049951 Genbank 17-Jan-2020 China Yunnan
MT012098 Genbank 27-Jan-2020 India Kerala
MN985325 Genbank 19-Jan-2020 USA Washington Returned to Washington State from Wuhan (35 years old male)
MN996531 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKO00000000
MN996530 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKN00000000
MN996529 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKM00000000
MN996528 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKL00000000
MN996527 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKK00000000
MN908947 Genbank 30-Dec-2019 China Wuhan
MT188341 Genbank 05-Mar-2020 USA Minnesota
MT188340 Genbank 07-Mar-2020 USA Minnesota
MT188339 Genbank 09-Mar-2020 USA Minnesota
MT184913 Genbank 24-Feb-2020 USA USA-CruiseA-26
MT184912 Genbank 17-Feb-2020 USA USA-CruiseA-25
MT184911 Genbank 17-Feb-2020 USA USA-CruiseA-24
MT184910 Genbank 18-Feb-2020 USA USA-CruiseA-23
MT184909 Genbank 21-Feb-2020 USA USA-CruiseA-22
MT184908 Genbank 21-Feb-2020 USA USA-CruiseA-21
MT184907 Genbank 18-Feb-2020 USA USA-CruiseA-19
LR757998 Genbank 26-Dec-2019 China Wuhan synonym: CNA0007332
LR757997 Genbank 31-Dec-2019 China Wuhan synonym: CNA0007333
LR757996 Genbank 01-Jan-2020 China Wuhan synonym: CNA0007334
LR757995 Genbank 05-Jan-2020 China Wuhan synonym: CNA0007335
MT159722 Genbank 21-Feb-2020 USA USA-CruiseA-6
MT159721 Genbank 21-Feb-2020 USA USA-CruiseA-5
MT159720 Genbank 21-Feb-2020 USA USA-CruiseA-4
MT159719 Genbank 18-Feb-2020 USA USA-CruiseA-3
MT159718 Genbank 18-Feb-2020 USA USA-CruiseA-2
MT159717 Genbank 17-Feb-2020 USA USA-CruiseA-1
MT159716 Genbank 24-Feb-2020 USA USA-CruiseA-18
MT159715 Genbank 24-Feb-2020 USA USA-CruiseA-17
MT159714 Genbank 18-Feb-2020 USA USA-CruiseA-16
MT159713 Genbank 18-Feb-2020 USA USA-CruiseA-15
MT159712 Genbank 25-Feb-2020 USA USA-CruiseA-14
MT159711 Genbank 20-Feb-2020 USA USA-CruiseA-13
MT159710 Genbank 17-Feb-2020 USA USA-CruiseA-9
MT159709 Genbank 20-Feb-2020 USA USA-CruiseA-12
MT159708 Genbank 17-Feb-2020 USA USA-CruiseA-11
MT159707 Genbank 17-Feb-2020 USA USA-CruiseA-10
MT159706 Genbank 17-Feb-2020 USA USA-CruiseA-8
MT159705 Genbank 17-Feb-2020 USA USA-CruiseA-7
MT118835 Genbank 23-Feb-2020 USA California
MT106054 Genbank 11-Feb-2020 USA Texas
MT106053 Genbank 10-Feb-2020 USA California
MT106052 Genbank 06-Feb-2020 USA California
MT044258 Genbank 27-Jan-2020 USA California
MT044257 Genbank 28-Jan-2020 USA Illinois
MT039888 Genbank 29-Jan-2020 USA Massachusetts
MT039887 Genbank 31-Jan-2020 USA Wisconsin
MT039890 Genbank Jan-2020 South Korea
MT039873 Genbank 20-Jan-2020 China Hangzhou synonym: GWHABKS00000000
MT027064 Genbank 29-Jan-2020 USA California
MT027063 Genbank 29-Jan-2020 USA California
MT027062 Genbank 29-Jan-2020 USA California
MT020881 Genbank 25-Jan-2020 USA Washington
MT020880 Genbank 25-Jan-2020 USA Washington
MT019533 Genbank 01-Jan-2020 China Wuhan synonym: GWHABKJ00000000
MT019532 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKI00000000
MT019531 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKH00000000
MT019530 Genbank 30-Dec-2019 China Wuhan synonym: GWHABKG00000000
MT019529 Genbank 23-Dec-2019 China Wuhan synonym: GWHABKF00000000
MT007544 Genbank 25-Jan-2020 Australia Victoria
MN997409 Genbank 22-Jan-2020 USA Arizona
MN994468 Genbank 22-Jan-2020 USA California
MN994467 Genbank 23-Jan-2020 USA California
MN988713 Genbank 21-Jan-2020 USA Illinois
MN988669 Genbank 02-Jan-2020 China Wuhan
MN988668 Genbank 02-Jan-2020 China Wuhan
MN975262 Genbank 11-Jan-2020 China Shenzhen Traveler from Shenzhen to Wuhan (10 years old male)
MN938384 Genbank 10-Jan-2020 China Shenzhen Traveler from Shenzhen to Wuhan (66 years old male)
LC521925 Genbank 25-Jan-2020 Japan Aichi
LC522975 Genbank 31-Jan-2020 Japan Tokyo
LC522974 Genbank 31-Jan-2020 Japan Tokyo
LC522973 Genbank 29-Jan-2020 Japan Tokyo
LC522972 Genbank 29-Jan-2020 Japan Kyoto
MN996532 Genbank 24-Jul-2013 China Bat (Rhinolophus affinis) coronavirus RaTG13, synonym: GWHABKP00000000
MG772933 Genbank Feb-2017 China Bat (Rhinolophus sinicus) SARS-like coronavirus

Meta data were supplemented from National Genomics Data Center (https://bigd.big.ac.cn/search).

Summary of parsimony-informative sites

                                       1111111111111111111111111111222222222222222222222222222222222222222
                111222333445555666678890011223444455566777777788899001134445555556666777777888888888889999                                         Sample Collection Date
             468039046014240057368946742303120478837989233478807866263740363566891779233569001368888880135
             913591646371306878191970873182110010726281427745863748698003293658174233728236794155678889802 - 2019 -||------------------------------------------- 2020 --------------------------------------------
             043972162771622424039692272930136885740772763478406754826734549358094906674554794174381235837   30-Dec     10-Jan    20-Jan    30-Jan     10-Feb    20-Feb   29-Feb    10-Mar    20-Mar    30-Mar        State/City
---------------------------------------------------------------------------------------------------------- -------|----------|---------|---------|----------|---------|--------|---------|---------|---------|---- ---------------------
MN908947.3   TGTCGCCTCCCCATGAGCCAGTAGCTCCGTGCTCGCCCGTCGTCCCCAACTCGGACCCACAACGTCCGGTGCCGTACCGCTCCCCGGGGCACG        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT019529.1   ............................................................................................. ●      |          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
LR757998.1   .............................................................................................    ●   |          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN996528.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN996530.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT019530.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT019532.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT291827.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT291829.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT291830.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN996529.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN996531.1   .............................................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
LR757996.1   .............................................................................................        | ●        |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT019533.1   .............................................................................................        | ●        |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN988668.1   .............................................................................................        |  ●       |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN988669.1   .............................................................................................        |  ●       |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT093631.2   .............................................................................................        |        ● |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT039873.1   .............................................................................................        |          |         ●         |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253701.1   .............................................................................................        |          |         |●        |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253708.1   .............................................................................................        |          |         |●        |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253709.1   .............................................................................................        |          |         |●        |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253710.1   .............................................................................................        |          |         |●        |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253702.1   .............................................................................................        |          |         |●        |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253705.1   .............................................................................................        |          |         | ●       |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253696.1   .............................................................................................        |          |         |  ●      |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253697.1   .............................................................................................        |          |         |  ●      |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253698.1   .............................................................................................        |          |         |  ●      |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253699.1   .............................................................................................        |          |         |   ●     |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253700.1   .............................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT192759.1   .............................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇹🇼 
MT253703.1   .............................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253704.1   .............................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT253707.1   .............................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Hangzhou
MT291835.1   .............................................................................................        |          |         |      ●  |          |         |        |         |         |         |     🇨🇳 Beijing
MT044258.1   .............................................................................................        |          |         |      ●  |          |         |        |         |         |         |     🇺🇸 California
MT121215.1   .............................................................................................        |          |         |         |  ●       |         |        |         |         |         |     🇨🇳 Shanghai
MT066176.1   .............................................................................................        |          |         |         |     ●    |         |        |         |         |         |     🇹🇼 Taipei
MT118835.1   .............................................................................................        |          |         |         |          |         |  ●     |         |         |         |     🇺🇸 California
MT304482.1   .............................................................................................        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Illinois
MT188340.1   .............................................................................................        |          |         |         |          |         |        |      ●  |         |         |     🇺🇸 Minnesota
LC534419.1   .............................................................................................        |          |         |         |          |         |        |        ●|         |         |     🇯🇵 Kanagawa
MT262993.1   .............................................................................................        |          |         |         |          |         |        |         | ●       |         |     🇵🇰 Khyber Pakhtunkhwa
LC521925.1   .....T.......................................................................................        |          |         |    ●    |          |         |        |         |         |         |     🇯🇵 Aichi
MT019531.1   .....................C.......................................................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT192772.1   ..........................T..................................................................        |          |         | ●       |          |         |        |         |         |         |     🇻🇳 Ho Chi Minh
MT192773.1   ..........................T..................................................................        |          |         | ●       |          |         |        |         |         |         |     🇻🇳 Ho Chi Minh
LC528232.1   ............................T................................................................        |          |         |         |          ●         |        |         |         |         |     🇯🇵 Kanagawa
LC528233.1   ............................T................................................................        |          |         |         |          ●         |        |         |         |         |     🇯🇵 Kanagawa
LC534418.1   ............................T................................................................        |          |         |         |          |   ●     |        |         |         |         |     🇯🇵 Kanagawa
MT276328.1   ............................T................................................................        |          |         |         |          |         |      ● |         |         |         |     🇺🇸 Oregon
MT276597.1   ............................T................................................................        |          |         |         |          |         |        |         |         |         |     🇮🇱 
MT240479.1   ....A.......................T................................................................        |          |         |         |          |         |        |   ●     |         |         |     🇵🇰 Gilgit
MT320891.1   ....A.......................T................................................................        |          |         |         |          |         |        |        ●|         |         |     🇮🇷 
MT276324.1   ..................................T..........................................................        |          |         |         |          |         |     ●  |         |         |         |     🇺🇸 California
MT276325.1   ..................................T..........................................................        |          |         |         |          |         |      ● |         |         |         |     🇺🇸 Washington
MT259230.1   ............................................T................................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Wuhan
MT012098.1   ............................................T................................................        |          |         |      ●  |          |         |        |         |         |         |     🇮🇳 Kerala
MT039887.1   ............................................T................................................        |          |         |         |●         |         |        |         |         |         |     🇺🇸 Wisconsin
MT259231.1   .......................................................T.....................................        |          |         |    ●    |          |         |        |         |         |         |     🇨🇳 Wuhan
MT259228.1   .......................................................T.....................................        |          |         |     ●   |          |         |        |         |         |         |     🇨🇳 Wuhan
MT259229.1   .......................................................T.....................................        |          |         |     ●   |          |         |        |         |         |         |     🇨🇳 Wuhan
MT259227.1   .......................................................T.....................................        |          |         |     ●   |          |         |        |         |         |         |     🇨🇳 Wuhan
MT020781.2   .........................................................T...................................        |          |         |        ●|          |         |        |         |         |         |     🇫🇮 Lapland
MT027064.1   .........................................................T...................................        |          |         |        ●|          |         |        |         |         |         |     🇺🇸 California
MT072688.1   ...........................................................T.................................        |          |  ●      |         |          |         |        |         |         |         |     🇳🇵 Kathmandu
MT291828.1   ............................................................G................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MN996527.1   ............................................................G................................        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT106053.1   ............................................................G................................        |          |         |         |          ●         |        |         |         |         |     🇺🇸 California
MT039890.1   ....................................................................T........................        |          |         |         |          |         |        |         |         |         |     🇰🇷 
MN994468.1   ....................................................................T........................        |          |         | ●       |          |         |        |         |         |         |     🇺🇸 California
MT007544.1   ....................................................................T........................        |          |         |    ●    |          |         |        |         |         |         |     🇦🇺 Victoria
MT093571.1   ....................................................................T........................        |          |         |         |       ●  |         |        |         |         |         |     🇸🇪 
MT292572.1   ............................T.......................................T........................        |          |         |         |          |         |        |         ●         |         |     🇪🇸 Valencia
MT281577.1   ............................T.......................................T........................        |          |         |         |          |         |        |         ●         |         |     🇨🇳 Fuyang
MT304487.1   ............................T......T................................T........................        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Oregon
MT126808.1   ............................T......T......C.........................T........................        |          |         |         |          |         |       ●|         |         |         |     🇧🇷 Sao Paulo
MT246454.1   ............................T......T......C.........................T........................        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT259267.1   ............................T......T......C.........................T........................        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT259285.1   ............G...............T......T............................C...T........................        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT263404.1   ............G...............T......T............................C...T........................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT304474.1   ................T...........T......T................................T............T...........        |          |         |         |          |         |      ● |         |         |         |     🇰🇷 
MT304475.1   ................T...........T......T................................T............T...........        |          |         |         |          |         |        ●         |         |         |     🇰🇷 
MT304476.1   ................T...........T......T................................T............T...........        |          |         |         |          |         |        ●         |         |         |     🇰🇷 
MT163716.1   .......C...T....T...........T......T................................T........................        |          |         |         |          |         |      ● |         |         |         |     🇺🇸 Washington
MT276326.1   .......C...T....T...........T......T................................T........................        |          |         |         |          |         |        ●         |         |         |     🇺🇸 Georgia
MT259226.1   ..........................................................................C..................        |          ●         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
MT263429.1   ...................................................................................T.........        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT027062.1   .A.............G...................................................................T.........        |          |         |        ●|          |         |        |         |         |         |     🇺🇸 California
MT027063.1   .A.............G...................................................................T.........        |          |         |        ●|          |         |        |         |         |         |     🇺🇸 California
MT123290.1   .....................................T.....................................................T.        |          |         |         |     ●    |         |        |         |         |         |     🇨🇳 Guangzhou
LC529905.1   .....................................T............................G........................T.        |          |         |         |          |         |        |         |         |         |     🇯🇵 Tokyo
LC522972.1   .....................................T............................G........................T.        |          |         |        ●|          |         |        |         |         |         |     🇯🇵 Kyoto
MT123291.2   ....................T.......................T...............................................A        |          |         |        ●|          |         |        |         |         |         |     🇨🇳 Guangzhou
MT123293.2   ....................TC......................T...............................................A        |          |         |        ●|          |         |        |         |         |         |     🇨🇳 Guangzhou
MT192765.1   .........T.......................T........................G..................................        |          |         |         |          |         |        |         |●        |         |     🇺🇸 California
MT263438.1   .........T.......................T........................G..................................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT320538.1   .........T.......................T...T....................G..................................        |          |         |         |          |         |        |         |         |         |     🇫🇷 
MT276323.1   .........T.......................T....................G...G..................................        |          |         |         |          |         |       ●|         |         |         |     🇺🇸 Rhode Island
MT304488.1   .........T.......................T....................G...G..................................        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Rhode Island
MT292569.1   .........T.......................T....................G...G..................................        |          |         |         |          |         |        |        ●|         |         |     🇪🇸 Valencia
MT293219.1   .........T............G..........T....................G...G..................................        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263433.1   .........T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT304490.1   .........T.......................T.................T......G....T.............................        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Texas
MT251974.1   .........T.......................T.................T......G....T.............................        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT246480.1   .........T.......................T.................T......G....T.............................        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT293197.1   .........T.......................T.................T......G....T.............................        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
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MT308702.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |         |     🇺🇸 North Carolina
MT304486.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        | ●       |         |         |     🇺🇸 New York
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MT293214.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293215.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
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MT263394.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         | ●       |     🇺🇸 Washington
MT263465.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263468.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263390.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263391.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263417.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263432.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263437.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263442.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263446.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263439.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263408.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263428.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT293178.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |     ●   |     🇺🇸 Washington
MT293174.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |      ●  |     🇺🇸 Washington
MT293195.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |       ● |     🇺🇸 Washington
MT293173.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |         ●     🇺🇸 Washington
MT293175.1   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |         ●     🇺🇸 Washington
MT300186.2   ...T.....T.......................T........................G....T.............................        |          |         |         |          |         |        |         |         |         |  ●  🇺🇸 North Carolina
MT259286.1   ...T.....T....................A..T........................G....T.............................        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT259261.1   ...T.....T....................A..T........................G....T.............................        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT293189.1   ...T.....T.......................T....A...................G....T.............................        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT293205.1   ...T.....T.......................T....A...................G....T.............................        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT251976.1   ...T.....T.......................T.......T................G....T.............................        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT263467.1   ...T.....T.......................T.......T................G....T.............................        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263392.1   ...T.....T.......................T.......T................G....T.............................        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT304484.1   ...T.....T......................CT........................G....T.T...........................        |          |         |         |          |         |        ●         |         |         |     🇺🇸 New Hampshire
MT304485.1   ...T.....T......................CT........................G....T.T...........................        |          |         |         |          |         |        | ●       |         |         |     🇺🇸 New Hampshire
MT259249.1   ...T.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259235.1   ...T.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT293182.1   ...T.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263415.1   ...T.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT246453.1   ..CT.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259244.1   ..CT.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT258378.1   ..CT.....T.......................T........................G....T.............T...............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 California
MT259243.1   ...T.....T.................T.....T........................G....T.............T...............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246484.1   ...T.....T.................T.....T........................G....T.............T...............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT293220.1   ...T.....T.................T.....T........................G....T.............T...............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263406.1   ...T.....T.................T.....T........................G....T.............T...............        |          |         |         |          |         |        |         |         |●        |     🇺🇸 Washington
MT259256.1   ...T.....T.......................T........................G....T.............T.T.............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259258.1   ...T.....T.......................T........................G....T.............T.T.............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT293161.1   ...T.....T..................T....T........................G....T.................T...........        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT276598.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |         |         |     🇮🇱 
MT276329.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |       ●|         |         |         |     🇺🇸 Florida
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MT276327.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        ●         |         |         |     🇺🇸 Georgia
MT304479.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |  ●      |         |         |     🇺🇸 Georgia
MT263074.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         ●         |         |     🇵🇪 
MT246470.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
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MT246451.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259250.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT293209.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT263402.1   .........T.......................T........................G...........................AAC....        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT291826.1   ........................T.......................................................C............        ●          |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
LR757995.1   ........................T.......................................................C............        |     ●    |         |         |          |         |        |         |         |         |     🇨🇳 Wuhan
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MT291836.1   ........................T.......................................................C............        |          |         |        ●|          |         |        |         |         |         |     🇨🇳 Beijing
MT066175.1   ........................T.......................................................C............        |          |         |         |●         |         |        |         |         |         |     🇹🇼 Taipei
MT050493.1   ........................T.......................................................C............        |          |         |         |●         |         |        |         |         |         |     🇮🇳 Kerala
MN985325.1   ........................T........................T..............................C............        |          |        ●|         |          |         |        |         |         |         |     🇺🇸 Washington
MT233526.1   ........................T........................T..............................C............        |          |        ●|         |          |         |        |         |         |         |     🇺🇸 Washington
MT246667.1   ........................T........................T..............................C............        |          |        ●|         |          |         |        |         |         |         |     🇺🇸 Washington
MT020880.1   ........................T........................T..............................C............        |          |         |    ●    |          |         |        |         |         |         |     🇺🇸 Washington
MT020881.1   ........................T........................T..............................C............        |          |         |    ●    |          |         |        |         |         |         |     🇺🇸 Washington
MT106052.1   ........................T.......................................................C....A.......        |          |         |         |      ●   |         |        |         |         |         |     🇺🇸 California
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MT135041.1   .............CT.........T.......................................................C............        |          |         |     ●   |          |         |        |         |         |         |     🇨🇳 Beijing
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MT291834.1   .............CT.........T.......................................................C............        |          |         |       ● |          |         |        |         |         |         |     🇨🇳 Beijing
MT049951.1   ........................T...C...................................................C............        |          |      ●  |         |          |         |        |         |         |         |     🇨🇳 Yunnan
MT226610.1   ......................G.T...T...................................................C............        |          |         ●         |          |         |        |         |         |         |     🇨🇳 
MN994467.1   ........................T..................................T.........C........C.C............        |          |         |  ●      |          |         |        |         |         |         |     🇺🇸 California
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MT292571.1   ........................TA.........T...............................T............C.T.T........        |          |         |         |          |         |        |        ●|         |         |     🇪🇸 Valencia
MT292573.1   ........................TA.........T...............................T............C.T.T........        |          |         |         |          |         |        |        ●|         |         |     🇪🇸 Valencia
MT044257.1   A.........T.............T..................................T.........C........C.C............        |          |         |       ● |          |         |        |         |         |         |     🇺🇸 Illinois
MT304480.1   A.........T.............T.........................C........T.........C........C.C............        |          |         |         |          |         |        |  ●      |         |         |     🇺🇸 Georgia
MT304481.1   A.........T.............T.........................C........T.........C........C.C............        |          |         |         |          |         |        |   ●     |         |         |     🇺🇸 Georgia
MT263410.1   A.........T.............T.........................C........T.........C........C.C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT295465.1   A.........T.............T.........................C........T.........C........C.C............        |          |         |         |          |         |        |         |         |      ●  |     🇺🇸 
MT263384.1   A.........T.............T.........................C........T.........C......T.C.C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT259252.1   A.........T.............T.........................C..T.....T.........C......T.C.C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT308703.1   A.........T.............T.........................C..T.....T.........C......T.C.C............        |          |         |         |          |         |        |         |         |         |     🇺🇸 North Carolina
MT163717.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |       ●|         |         |         |     🇺🇸 Washington
MT163718.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        ●         |         |         |     🇺🇸 Washington
MT163719.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Washington
MT262915.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246461.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246466.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246479.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259266.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT259268.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262900.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262901.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262905.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262907.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262910.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262911.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262912.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262913.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262914.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262916.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262899.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246469.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT246474.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT259262.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT251977.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT259274.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT259275.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT246488.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT246468.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT251972.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT251978.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT259271.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT259245.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT259282.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT259280.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT259237.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259247.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259253.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259257.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259254.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259236.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT259241.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT293168.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293187.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293186.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293170.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT293181.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT293199.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293208.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293210.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293202.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293216.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT293206.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT263444.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         ●         |     🇺🇸 Washington
MT263403.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         ●         |     🇺🇸 Washington
MT263405.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |●        |     🇺🇸 Washington
MT263412.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         | ●       |     🇺🇸 Washington
MT263396.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         | ●       |     🇺🇸 Washington
MT263423.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263381.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263382.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263462.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263463.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263383.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263425.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263449.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263456.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263399.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263430.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263440.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263452.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263414.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT293185.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |       ● |     🇺🇸 Washington
MT293192.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |       ● |     🇺🇸 Washington
MT293188.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |       ● |     🇺🇸 Washington
MT293163.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |        ●|     🇺🇸 Washington
MT293157.1   ........................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |        ●|     🇺🇸 Washington
MT263434.1   .....T..................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT259276.1   ......T.................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT293177.1   ......T.................T.....................TG.T..............................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 
MT152824.1   .................T......T.....................TG.T..............................C............        |          |         |         |          |         |   ●    |         |         |         |     🇺🇸 Washington
MT163720.1   .................T......T.....................TG.T..............................C............        |          |         |         |          |         |        |●        |         |         |     🇺🇸 Washington
MT246455.1   .................T......T.....................TG.T..............................C............        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT293184.1   .................T......T.....................TG.T....................A.........C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT293211.1   .................T......T.....................TG.T....................A.........C............        |          |         |         |          |         |        |         |        ●|         |     🇺🇸 Washington
MT246477.1   ..................T.....T.....................TG.T..............................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT263424.1   ..................T.....T.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT246486.1   ..................T.....T.....................TG.T.......................T......C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT263398.1   ..................T.....T.....................TG.T.......................T......C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT293166.1   ...................G....T.....................TG.T............T.................C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293218.1   ...................G....T.....................TG.T............T.................C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263458.1   ...................G....T...........T.........TG.T..............................C.........T..        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263435.1   ...................G....T...........T.........TG.T..............................C.........T..        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263419.1   .......................AT.....................TG.T..............................C............        |          |         |         |          |         |        |         |         ●         |     🇺🇸 Washington
MT263464.1   .......................AT.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263400.1   .......................AT.....................TG.T..............................C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263416.1   ........................T...T.................TG.T..............................C............        |          |         |         |          |         |        |         |         |●        |     🇺🇸 Washington
MT263395.1   ........................T...T.................TG.T..............................C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT246475.1   ........................T...T...........T.....TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246471.1   ........................T...T.................TG.T........................C.....C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT246457.1   ........................T......T..............TG.T..............................C............        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT251980.1   ........................T......T..............TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246459.1   ........................T....................TTG.T..............................C............        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT246476.1   ........................T....................TTG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT188341.1   ........................T.....................TG.T......T.......................C............        |          |         |         |          |         |        |    ●    |         |         |     🇺🇸 Minnesota
MT188339.1   ........................T.....................TG.T......T.......................C............        |          |         |         |          |         |        |        ●|         |         |     🇺🇸 Minnesota
MT295464.1   ........................T.....................TG.T...........T..................C............        |          |         |         |          |         |        |         ●         |         |     🇺🇸 
MT259269.1   ........................T.....................TG.T...........T..................C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT293159.1   ........................T.....................TG.T...........T..................C............        |          |         |         |          |         |        |         |     ●   |         |     🇺🇸 Washington
MT246452.1   ........................T.....................TG.T.........................G....C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT246462.1   ........................T.....................TG.T.........................G....C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT293183.1   ........................T.....................TG.T.........................G....C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263457.1   ........................T.....................TG.T.........................G....C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263448.1   ........................T...............T.....TG.T.........................G....C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT246472.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         | ●       |         |     🇺🇸 Washington
MT262896.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262897.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262898.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262902.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262903.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262904.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262906.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262908.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT262909.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT293225.1   ........................T....C................TG.T..............................C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT246478.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT251975.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT246489.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT293179.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293190.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MT293194.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |       ● |         |     🇺🇸 Washington
MT263469.1   ........................T.....................TG.T........................C.....C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT246464.1   ........................T.....................TG.T......................T.C.....C............        |          |         |         |          |         |        |         |  ●      |         |     🇺🇸 Washington
MT263450.1   ........................T.....................TG.T......................T.C.....C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT263447.1   ........................T..............G......TG.T.....................T........C............        |          |         |         |          |         |        |         |   ●     |         |     🇺🇸 Washington
MT263388.1   ........................T..............G......TG.T.....................T........C............        |          |         |         |          |         |        |         |         |  ●      |     🇺🇸 Washington
MT263422.1   ........................T..............G......TG.T.....................T........C............        |          |         |         |          |         |        |         |         |   ●     |     🇺🇸 Washington
MT259287.1   ........................T..................T..TGGT..T...........................C............        |          |         |         |          |         |        |         |    ●    |         |     🇺🇸 Washington
MT293169.1   ........................T..................T..TGGT..T...........................C............        |          |         |         |          |         |        |         |      ●  |         |     🇺🇸 Washington
MN938384.1   ........................T.......................................................C........T...        |          ●         |         |          |         |        |         |         |         |     🇨🇳 Shenzhen
MN975262.1   ........................T.......................................................C........T...        |          |●        |         |          |         |        |         |         |         |     🇨🇳 Shenzhen
MT291831.1   ........................T.......................................................C........T...        |          |         |   ●     |          |         |        |         |         |         |     🇨🇳 Beijing
MT106054.1   ........................T.......................................................C........T...        |          |         |         |          |●        |        |         |         |         |     🇺🇸 Texas
MN997409.1   ........................T...T...................................................C........T...        |          |         | ●       |          |         |        |         |         |         |     🇺🇸 Arizona
LC522973.1   ........T...............T.......................................................C........T...        |          |         |        ●|          |         |        |         |         |         |     🇯🇵 Tokyo
LC522974.1   ........T...............T.......................................................C........T...        |          |         |         |●         |         |        |         |         |         |     🇯🇵 Tokyo
LC522975.1   ........T...............T.......................................................C........T...        |          |         |         |●         |         |        |         |         |         |     🇯🇵 Tokyo
MN996532.1   .........T............C.T..............C....T....T.........T...A.......T........C........T...        |          |         |         |          |         |        |         |         |         |     🦇
MG772933.1   .....A....A..C....T...C.T.........ATTT.GT.............C..G.T...A.G..............C.A......T...        |          |         |         |          |         |        |         |         |         |     🦇

Summary of maximum-likelihood phylogenetic analyses

No. Data type Directory Partition Final LogLikelihood AIC score AICc score BIC socre # Free parameters
1 DNA univ/uni/ No partition -62657.326781 126830.653562 126871.180612 133107.078890 758
2 DNA univ/3rd/ Separate 3rd codon position and others -62080.032512 125676.065024 125716.592074 131952.490352 758
3 DNA univ/sep/ Separate each codon position -61674.930991 124881.861982 124923.260094 131224.529266 766
4 DNA part/uni/ Separate each ORF -63290.960535 128199.921070 128246.164321 134898.638867 809
5 DNA part/3rd/ Separate each ORF, 3rd codon position and others -59946.218274 121618.436548 121671.155606 128764.287548 863
6 DNA part/sep/ Separate each ORF, each codon position -59816.294995 121420.589990 121477.224333 128823.128570 894

Release notes

Release Date Contents
28-Feb-2020 initial release
12-Mar-2020 update genome sequence data, improve parallelization efficiency and usability of the scripts
18-Mar-2020 update genome sequence data
20-Mar-2020 update genome sequence data, remove USA-CruiseA data from the analyses
23-Mar-2020 update genome sequence data
31-Mar-2020 update genome sequence data
05-Apr-2020 update genome sequence data
15-Apr-2020 update genome sequence data, change MSA software, disable AA-based phylogenetic analyses
01-May-2020 update genome sequence data

License

All in-house scripts in script/ direcory are released under the MIT license. See also script/LICENSE.

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SARS-CoV-2 genome sequence data analyses

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