This repo contains my final project for BF550. In this project, I replicate two figures for Meng et al., 2024 using available data sets and report how it was done and the main findings from these figures.
- Creation of UMAP plot from analyticaly determined significant parameters
- Creation of volcano plot from analyticaly determined significant parameters
├── data/ # Processed datasets used for analysis and plot creation
├── BF550_Project_2_Notebook.ipynb # Jupyter notebook containing analaysis and creation of plots
├── BF550_Project_2_Report.pdf # Report outlining introduction of the paper i used, my analysis processes, and results
└── README.md # Project documentation (this file)
Meng, L., Jin, H., Burak Yulug, Ozlem Altay, Li, X., Lutfu Hanoglu, Seyda Cankaya, Coskun, E., Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Saeed Shoaie, Hasan Turkez, Nielsen, J., Zhang, C., Borén, J., Mathias Uhlén, & Adil Mardinoglu. (2024). Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer’s disease. Alzheimer S Research & Therapy, 16(1). https://doi.org/10.1186/s13195-024-01578-6