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47 changes: 47 additions & 0 deletions .github/actions/spelling/allow/terms.txt
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Expand Up @@ -83,3 +83,50 @@
youtu
youtube
zenodo
ACAT
ADSIAMUQ
AKMODE
arxiv
BKACAT
BKPy
CARTDIGITALTWIN
chep
CSSI
Ehrig
EUROLLVM
FFLLVM
FOUNDSCIROOFIT
FOURTHMODEBDM
groundbreaking
GSACAT
GSCHEP
GSMODE
HOMMEXX
IDD
interoperate
IPDPS
jacobians
LIGO
MAMODE
meetup
metaprogramming
Miapb
multilanguage
omnidisciplinary
optimisation
optimisations
personalised
preslist
pubpic
recomputations
ROOFIT
Sacado
SKLLVM
SNL
SNSFPI
supercomputing
VVACAT
VVCR
VVLLVM
VVMODE
VVSNL

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15 changes: 15 additions & 0 deletions _data/preslist.yml
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- title: "From measurement to decision: a tissue-aware digital-twin platform for CAR T cell dosimetry"
description: |
Agent-based models (ABM) are powerful tools for digital twins in personalised medicine, enabling simulation of CAR T cell dynamics and therapy responses. CARTopiaX, implemented in the BioDynaMo engine, supports rapid, high-performance 3D simulations of tumour growth and CAR T cell administration, reproducing cellular dynamics with high fidelity and offering an accessible interface to explore treatment dose, fractionation, and administration routes.

Tissue-resolved wet-lab measurements of CAR T cell functionality and persistence across organs are critical to guide and validate ABM, supporting the evaluation of different dosimetry strategies, including single and multiple dosing to prevent T cell hypofunction. Preliminary benchmarks show that CARTopiaX runs simulations in approximately half the time of the previously published ABM.

This tissue-aware digital-twin framework provides fast, interpretable, and actionable insights, facilitating hypothesis testing, reducing exploratory animal use, and guiding CAR T cell dosimetry in preclinical studies.
location: "[Foundations of Oncological Digital Twins workshop in Cambridge](https://www.newton.ac.uk/event/ooew07/)"
date: 2025-09-19
speaker: Luciana Melina Luque
id: "CARTDIGITALTWIN2025CAMBRIDGE"
artifacts: |
[Link to Poster](/assets/presentations/LMLuque_Poster_19_09_2025.pdf)
highlight: 1

- title: "Bringing Automatic Differentiation to CUDA with Compiler-Based Source Transformations"
description: |
GPUs have become increasingly popular for their ability to perform parallel operations efficiently, driving interest in General-Purpose GPU Programming. Scientific computing, in particular, stands to benefit greatly from these capabilities. However, parallel programming systems such as CUDA introduce challenges for code transformation tools due to their reliance on low-level hardware management primitives. These challenges make implementing automatic differentiation (AD) for parallel systems particularly complex.
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