Analysis of Whole-Cell Recordings in Python

The attached Jupyter notebook wcr-python analyzes whole-cell patch-clamp recordings in current-clamp mode to:

• Open .abf files from Axon pClamp using the pyABF package.
• Plot traces.
• Detect action potentials and analyze firing features, adapting the IPFX package from the Allen Institute.
• Extract passive membrane properties using a custom function.
• Measure sag properties using a custom function.

If you use or adapt this notebook, please credit the main libraries and cite the following paper:

TBA

Further Resources

• Patch-clamp data analysis in Python and Clampfit. Tutorials and information.
• Neuroscience Notebook Templates. Basic templates for processing and analyzing neuroscience data.