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In a previous comment it was mentioned that data URIs don't work for the cram format. Data URIs seem to work just fine for the cram format when removing the check that disables it, see the provided test case. You must provide an indexURI (which can also be a data URI), but I guess that is always the case for cram alignment tracks?
This makes sense since the underlying code in igv-utils handles data retrieval for both data URIs and other URIs.
We're currently using embedded bams in offline html files and would be really happy if we could switch to cram to reduce file size.