-
Notifications
You must be signed in to change notification settings - Fork 16
Commit
This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository.
Merge pull request #683 from isb-cgc/staging
Staging
- Loading branch information
Showing
5 changed files
with
164 additions
and
0 deletions.
There are no files selected for viewing
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,29 @@ | ||
***************** | ||
Exceptional Responders Data Set | ||
***************** | ||
|
||
About Exceptional Responders | ||
------------------------------------------------------------------------ | ||
|
||
The Exceptional Responders Initiative is a pilot study to investigate the underlying molecular factors driving exceptional treatment responses of cancer patients to drug therapies. | ||
|
||
About Exceptional Responders Data | ||
--------------------------------------------------------------------------------- | ||
|
||
Exceptional Responders has one project EXCEPTIONAL_RESPONDERS-ER with 84 cases spanning nine disease types and 20 primary sites. Data categories include sequencing reads, transcriptome profiling and simple nucleotide variation. | ||
|
||
For more information on Exceptional Responders data, please refer to the site below: | ||
|
||
- `GDC Data Portal <https://portal.gdc.cancer.gov/projects?filters=%7B%22op%22%3A%22and%22%2C%22content%22%3A%5B%7B%22op%22%3A%22in%22%2C%22content%22%3A%7B%22field%22%3A%22projects.program.name%22%2C%22value%22%3A%5B%22EXCEPTIONAL_RESPONDERS%22%5D%7D%7D%5D%7D>`_ | ||
|
||
|
||
Accessing the Exceptional Responders Data in Google BigQuery | ||
------------------------------------------------ | ||
|
||
ISB-CGC has Exceptional Responders data, such as clinical, stored in Google BigQuery tables. Information about these tables can be found using the `ISB-CGC BigQuery Table Search <https://isb-cgc.appspot.com/bq_meta_search/>`_ with EXCEPTIONAL RESPONDERS selected for filter PROGRAM. | ||
To learn more about this tool, see the `ISB-CGC BigQuery Table Search documentation <../BigQueryTableSearchUI.html>`_. | ||
|
||
The Exceptional Responders tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the `ISB-CGC BigQuery Tables documentation <../BigQuery.html>`_. | ||
|
||
- Data set ``isb-cgc-bq.EXC_RESPONDERS`` contains the latest tables for each data type. | ||
- Data set ``isb-cgc-bq.EXC_RESPONDERS_versioned`` contains previously released tables, as well as the most current table. |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,28 @@ | ||
***************** | ||
MP2PRT Data Set | ||
***************** | ||
|
||
About MP2PRT | ||
------------------------------------------------------------------------ | ||
|
||
The Molecular Profiling to Predict Response to Treatment (MP2PRT) program is part of the NCI's Cancer Moonshot Initiative. This study "Identification of Genetic Changes Associated with Relapse and/or Adaptive Resistance in Patients Registered as Favorable Histology Wilms Tumor on AREN03B2" performs genomic characterization on trio cases (normal tissue, tumor tissue at time of diagnosis, tumor tissue at time of relapse) from patients who relapsed with Favorable Histology Wilms Tumor. | ||
|
||
About MP2PRT Data | ||
--------------------------------------------------------------------------------- | ||
|
||
The MP2PRT data set includes one project MP2PRT-WT with 52 cases. Data categories include sequencing reads, transcriptome profiling, simple nucleotide variation and copy number variation. | ||
|
||
For more information on MP2PRT data, please refer to the site below: | ||
|
||
- `GDC Data Portal <https://portal.gdc.cancer.gov/projects?filters=%7B%22op%22%3A%22and%22%2C%22content%22%3A%5B%7B%22op%22%3A%22in%22%2C%22content%22%3A%7B%22field%22%3A%22projects.program.name%22%2C%22value%22%3A%5B%22MP2PRT%22%5D%7D%7D%5D%7D>`_ | ||
|
||
|
||
Accessing the MP2PRT Data in Google BigQuery | ||
------------------------------------------------ | ||
|
||
ISB-CGC has MP2PRT data, such as clinical, stored in Google BigQuery tables. Information about these tables can be found using the `ISB-CGC BigQuery Table Search <https://isb-cgc.appspot.com/bq_meta_search/>`_ with MP2PRT selected for filter PROGRAM. To learn more about this tool, see the `ISB-CGC BigQuery Table Search documentation <../BigQueryTableSearchUI.html>`_. | ||
|
||
The MP2PRT tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the `ISB-CGC BigQuery Tables documentation <../BigQuery.html>`_. | ||
|
||
- Data set ``isb-cgc-bq.MP2PRT`` contains the latest tables for each data type. | ||
- Data set ``isb-cgc-bq.MP2PRT_versioned`` contains previously released tables, as well as the most current table. |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,42 @@ | ||
***************** | ||
REBC Data Set | ||
***************** | ||
|
||
About REBC | ||
------------------------------------------------------------------------ | ||
|
||
REBC studies comprehensive genomic characterization of radiation-related papillary thyroid cancer in the Ukraine after the 1986 Chernobyl nuclear power plan accident. This accident released radioactive contaminants into the surrounding areas in Ukraine, Belarus, and Russia, causing an increased occurrence of thyroid cancer among individuals who were children at the time of the accident or born not long afterwards. | ||
|
||
About REBC | ||
--------------------------------------------------------------------------------- | ||
|
||
The REBC data set includes one project REBC-THYR with 440 cases. Data categories include sequencing reads, transcriptome profiling, simple nucleotide variation and copy number variation. | ||
|
||
For more information on REBC data, please refer to the site below: | ||
|
||
- `GDC Data Portal <https://portal.gdc.cancer.gov/projects?filters=%7B%22op%22%3A%22and%22%2C%22content%22%3A%5B%7B%22op%22%3A%22in%22%2C%22content%22%3A%7B%22field%22%3A%22projects.program.name%22%2C%22value%22%3A%5B%22REBC%22%5D%7D%7D%5D%7D>`_ | ||
|
||
Accessing the REBC Data on the Cloud | ||
------------------------------------------------------------------------------------------- | ||
|
||
Besides accessing the files on the GDC Data Portal, you can also access them from the GDC Google Cloud Storage Bucket, which means that you don’t need to download them to perform analysis. ISB-CGC stores the cloud file locations in tables in the ``isb-cgc-bq.GDC_case_file_metadata`` data set in BigQuery. | ||
|
||
- To access these metadata files, go to the Google BigQuery console. | ||
- Perform SQL queries to find the REBC files. Here is an example: | ||
|
||
.. code-block:: sql | ||
SELECT active.*, file_gdc_url | ||
FROM `isb-cgc-bq.GDC_case_file_metadata.fileData_active_current` as active, `isb-cgc-bq.GDC_case_file_metadata.GDCfileID_to_GCSurl_current` as GCSurl | ||
WHERE program_name = 'REBC' | ||
AND active.file_gdc_id = GCSurl.file_gdc_id | ||
Accessing the REBC Data in Google BigQuery | ||
------------------------------------------------ | ||
|
||
ISB-CGC has REBC data, such as clinical and metadata, stored in Google BigQuery tables. Information about these tables can be found using the `ISB-CGC BigQuery Table Search <https://isb-cgc.appspot.com/bq_meta_search/>`_ with REBC selected for filter PROGRAM. To learn more about this tool, see the `ISB-CGC BigQuery Table Search documentation <../BigQueryTableSearchUI.html>`_. | ||
|
||
The REBC tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the `ISB-CGC BigQuery Tables documentation <../BigQuery.html>`_. | ||
|
||
- Data set ``isb-cgc-bq.REBC`` contains the latest tables for each data type. | ||
- Data set ``isb-cgc-bq.REBC_versioned`` contains previously released tables, as well as the most current table. |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,43 @@ | ||
***************** | ||
TRIO Data Set | ||
***************** | ||
|
||
About TRIO | ||
------------------------------------------------------------------------ | ||
|
||
The Ukrainian National Research Center for Radiation Medicine Trio Study contains epidemiologic data of trios of parents (exposed to the radiation from the Chernobyl accident) and their unexposed offspring. The purpose of the study is to investigate the transgenerational effects following nuclear accidents to understand the consequences of parental exposure to ionizing radiation. | ||
|
||
|
||
About the TRIO Data | ||
--------------------------------------------------------------------------------- | ||
|
||
The TRIO data set includes whole genome sequencing (WGS) sequencing reads for 339 cases in the project TRIO-CRU. | ||
|
||
For more information on TRIO data, please refer to the site below: | ||
|
||
- `GDC Data Portal <https://portal.gdc.cancer.gov/projects?filters=%7B%22op%22%3A%22and%22%2C%22content%22%3A%5B%7B%22op%22%3A%22in%22%2C%22content%22%3A%7B%22field%22%3A%22projects.program.name%22%2C%22value%22%3A%5B%22TRIO%22%5D%7D%7D%5D%7D>`_ | ||
|
||
Accessing the TRIO Data on the Cloud | ||
------------------------------------------------------------------------------------------- | ||
|
||
Besides accessing the files on the GDC Data Portal, you can also access them from the GDC Google Cloud Storage Bucket, which means that you don’t need to download them to perform analysis. ISB-CGC stores the cloud file locations in tables in the ``isb-cgc-bq.GDC_case_file_metadata`` data set in BigQuery. | ||
|
||
- To access these metadata files, go to the Google BigQuery console. | ||
- Perform SQL queries to find the TRIO files. Here is an example: | ||
|
||
.. code-block:: sql | ||
SELECT active.*, file_gdc_url | ||
FROM `isb-cgc-bq.GDC_case_file_metadata.fileData_active_current` as active, `isb-cgc-bq.GDC_case_file_metadata.GDCfileID_to_GCSurl_current` as GCSurl | ||
WHERE program_name = 'TRIO' | ||
AND active.file_gdc_id = GCSurl.file_gdc_id | ||
Accessing the TRIO Data in Google BigQuery | ||
------------------------------------------------ | ||
|
||
ISB-CGC has TRIO data, such as clinical and metadata, stored in Google BigQuery tables. Information about these tables can be found using the `ISB-CGC BigQuery Table Search <https://isb-cgc.appspot.com/bq_meta_search/>`_ with TRIO selected for filter PROGRAM. To learn more about this tool, see the `ISB-CGC BigQuery Table Search documentation <../BigQueryTableSearchUI.html>`_. | ||
|
||
The TRIO tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the `ISB-CGC BigQuery Tables documentation <../BigQuery.html>`_. | ||
|
||
- Data set ``isb-cgc-bq.TRIO`` contains the latest tables for each data type. | ||
- Data set ``isb-cgc-bq.TRIO_versioned`` contains previously released tables, as well as the most current table. |