Identification of 13 independent genetic loci associated with cognitive resilience in healthy ageing in 330,097 individuals in the UK Biobank .
Code used to create the GWAS-by-subtraction of Resilience , and for follow-up analyses.
- Generation of initial GWAS of EY + Res and EY/NonRES and EY and RT for futher analysis (Generation_of_GWAS.sh)
- Code for GWAS-by-Subtration (GWAS-by-subtraction.sh)
- Calculation of sample size after GWAS-by-Subtration (GBS_sample_size.sh)
- Conditional analysis(Conditional_analysis.sh)
- FINEMAP (FINEMAP.sh)
- Drawing Venn diagram (Venn_diagram.sh)
- Magma analysis(MAGMA.sh)
- LD score regression analysis (LDSC.sh)
- Generalised Summary statistics-based Mendelian Randomisation (GSMR.sh)
- Removal of locus on chromosome 3 (GBS_minus_locus3.sh)
- GWAS of Resilience
During the couse of this analysis the terms used for the inputs and outputs to GWAS-by-Subtraction changed as follows: for RV read EY+Res and for V read EY/NonRes for res read Resilience and for var read EduYears analysis