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Poisson models for quantifying DNA copy-number from fluorescence in situ hybridisation of tissue sections

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FrenchFISH

FrenchFISH is an R package for for correcting spot counts used for quantifying DNA copy-number from fluorescence in situ hybridisation of tissue sections. It can correct either spot counts from manual counting, or from an automatic spot counting software. The underlying models used to correct these counts are Poissonian. Details can be found in this manuscript.

Installation

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("frenchFISH")

Getting Started

vignettes/frenchFISH.Rmd

Disclaimer

Note that this is prerelease software. Please use accordingly.

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Poisson models for quantifying DNA copy-number from fluorescence in situ hybridisation of tissue sections

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