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GUI Analysis Tools | ||
------------------ | ||
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.. toctree:: | ||
:maxdepth: 3 | ||
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guitools/funfit.rst | ||
guitools/runfit.rst | ||
guitools/mulfit.rst | ||
guitools/impedancetools.rst |
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.. _funfit: | ||
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FunctionFitter | ||
-------------- | ||
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A widget for graphing a parameterized function while exploring parameter | ||
variations. Also can adjust the parameters automatically to fit data. | ||
Function, parameters, independent variable can be specified by the user. | ||
This widget may be saved in a session. | ||
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The FunctionFitter starts out with entries for graphing a single exponential | ||
with two parameters. When a parameter value is changed the graph is replotted. | ||
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Plot | ||
~~~~ | ||
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Replots function with current arg values | ||
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Steps | ||
~~~~~ | ||
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Number of values of independent variable used in plot | ||
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IndependentVar | ||
~~~~~~~~~~~~~~ | ||
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Enter the name of independent variable in a | ||
string dialog. | ||
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Args | ||
~~~~ | ||
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Enter space separated names of parameters in a string dialog. | ||
Default value editors for these parameters will appear in the rightmost | ||
box. | ||
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Yexpr | ||
~~~~~ | ||
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Enter an expression involving the independent variable and the | ||
parameters (args). Any valid top level hoc expression is acceptable. | ||
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PraxisFit | ||
~~~~~~~~~ | ||
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Starts fitting the function to the data with respect to the DataWeights | ||
by adjusting the checked argument values. See :func:`fit_praxis` . | ||
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StopAtNextQuadForm | ||
~~~~~~~~~~~~~~~~~~ | ||
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Stop the praxis fitter when it finishes its current/next cycle. | ||
At this point it contains a computation of the quadratic form of the parameter | ||
phase space (printed in the terminal window). | ||
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Running | ||
~~~~~~~ | ||
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Checked when the praxis fitter is executing. | ||
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WatchTheFit | ||
~~~~~~~~~~~ | ||
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Plot the function on each call to the error function during fitting. | ||
Things are slower if this box is checked. | ||
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RoughFit | ||
~~~~~~~~ | ||
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Instead of fitting all the data according to the data weights, use | ||
only 5 equally spaced points in each of the two central data regions. | ||
Things can be much faster if this box is checked. | ||
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ArgValues | ||
~~~~~~~~~ | ||
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The values of the arguments are used in the plot. When a value | ||
is changed the function is replotted. When fit data is present, a | ||
checkbox is added to the left of each argument button. When the box is checked | ||
then the fitter adjusts the value for a best fit. When not checked the parameter | ||
is treated as a constant. | ||
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CurrentValuesAsDefault | ||
====================== | ||
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Resets the default values of the parameter field editors to their current values. | ||
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FittoData | ||
~~~~~~~~~ | ||
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ReadDataFile | ||
============ | ||
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Get data from a file. The format is the number of data points followed | ||
by pairs of x,y data. | ||
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CommonFunctionalForms | ||
===================== | ||
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FitCriterion | ||
============ | ||
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not implemented | ||
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ParameterRangeLimits | ||
==================== | ||
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Pops up a panel of parameters with their range limits. When | ||
the fitter calls the error function and one of the parameters is | ||
outside its range the error function will return a value of 1e6. | ||
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DataWeights | ||
=========== | ||
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Pops up a panel of data weight intervals and weights. The first interval | ||
ranges from the beginning of the data to the interval 1 endpoint. From | ||
the interval3 endpoint to the end of the data, the weight is 0. The entire | ||
interval is given the weight indicated. Intervals can be manipulated directly | ||
by the :guilabel:`AdjustWeightRegions` tool of the :guilabel:`Graph` menu. | ||
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SaveRestoreFunction | ||
=================== | ||
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Arg values and the y-expression can be saved in a list and restored by selection | ||
with a browser. | ||
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.. _attshape: | ||
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.. seealso: :ref:`impratio`, :ref:`impedance_impx`, :ref:`impedance_logavsx`, | ||
Impedance Tools | ||
--------------- | ||
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These tools plot various functions of :class:`Impedance` vs | ||
location and frequency. :ref:`impshape` is described below, but see also: | ||
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.. toctree:: :maxdepth: 1 | ||
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impratio.rst | ||
impedanx.rst | ||
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Each tool has three panels: The top | ||
panel contains button and menu controls specific to the tool. The | ||
middle panel displays a picture of the cell and marks the measurement | ||
and injection sites. The bottom panel displays the results of the | ||
impedance measurements. | ||
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The redraw button in the top panel forces a re-calculation of the results. | ||
This is useful if a parameter or state changes in the underlying model | ||
of the cell. The :menuselection:`Extras --> MovieMode` menu item recalculated the results | ||
for each step during a :ref:`runcontrol_initrun`. When selected, | ||
the :menuselection:`Extras --> AutoScale` rescales | ||
the results panel after each calculation. | ||
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The :guilabel:`Plot` menu specifies whether to plot log attenuation (default), | ||
input impedance, transfer impedance, or ``V(measure)/V(inject)`` | ||
Note: log attenuation is defined as ``ln( V(inject)/V(measure) )`` | ||
Input impedance is plotted with | ||
respect to the measurement site and the injection site is unused. | ||
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.. _impshape: | ||
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ImpShape | ||
~~~~~~~~ | ||
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Tool for generating the neuromorphic rendering, a picture of the | ||
neuron in which distance is scaled to represent the log of | ||
voltage attenuation. In this transform, | ||
long distance represents large attenuation. | ||
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The tool consists of three panels. The middle panel shows the normal | ||
unscaled shape of the neuron on which the user can select a measurement/injection | ||
site (default location is location 0 of the currently accessed section | ||
when the ImpShape object was created). The lower panel displays | ||
a neuromorphic rendering along with a unit attenuation scale bar. | ||
The upper control panel allows selection of the frequency at which to | ||
calculate the impedance and the direction of current flow, ``Vin/Vout``, | ||
with respect | ||
to the measurement/injection site. | ||
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When :guilabel:`Vin` is selected one can imagine that | ||
for every point on the cell, that point is voltage clamped to 1 mV and | ||
the voltage at the measurement site (0 end of the selected section in | ||
the lower panel) is recorded. The shape of the neuron | ||
is then plotted so that the distance between the | ||
voltage clamp site and the measurement site is the natural | ||
log of the attenuation | ||
factor, ``ln( V(inject)/V(measure) )`` | ||
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When :guilabel:`Vout` is selected, one can imagine that the selected position | ||
becomes voltage clamped to 1mV and the voltage at every other position | ||
on the cell is measured. | ||
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.. _impedanx: | ||
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.. _impedance_impx: | ||
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Impx | ||
---- | ||
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Tool for plotting voltage attenuation at a specific measurement/injection | ||
site as | ||
a function of selected path along the neuron at each point of which | ||
current is injected/measured. | ||
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Frequency (Hz) of injected current is specified in the "frequency" field | ||
editor. | ||
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The measurement/injection site is selected by first selecting the | ||
:guilabel:`measure/inject` item of the :guilabel:`SelectLocation` menu and then selecting a | ||
location on the neuron in the middle panel. A red dot denotes the | ||
measurement (Vin mode) location or the injection location (Vout mode). | ||
The end points of the path are selected by first | ||
selecting the "path start" or "path end" menu items and then selecting a | ||
location on the neuron in the middle panel. | ||
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The Vin and Vout radio buttons select whether the independent variable | ||
in the results panel refers to injection position or measurement | ||
position along the selected path. | ||
The x=0 coordinate in the results section refers to the point on the | ||
path that is closest to the root of the cell (The root is normally the | ||
soma). Negative abscissa values are on the path start side and | ||
positive values are on the path end side. | ||
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This tool uses the :class:`Impedance` class to calculate voltage | ||
attenuations. | ||
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.. _impedance_logavsx: | ||
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LogAvsX | ||
------- | ||
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Tool for plotting voltage attenuation at a specific measurement/injection | ||
site as a function of Every point on the cell where current is | ||
injected/measured. Abscissa in the results panel shows the distance | ||
of every point from the root of the cell (usually soma(0)). | ||
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When the Vin radio button is selected the measurement site is fixed | ||
(red dot) and the independent variable is the location of the injection | ||
site. When Vout is selected, the independent variable is the measurement | ||
location and the red dot refers to the fixed injection site. | ||
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In order to identify a particular section in the morphology panel | ||
with a particular line segment in the results panel one can: | ||
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1) In the results panel use the graph menu (right mouse button) to select | ||
the "ShowPosition" item. Then click (left mouse button) near the | ||
beginning, end, or segment center of one of the lines. This will color red both | ||
the line and the corresponding morphology section. | ||
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2) The meaning of the Section menu item in the morphology panel is | ||
determined by the :guilabel:`ShapeSelectAction` menu item in the control panel. | ||
When :guilabel:`MoveElectrode` is selected (and the Section menu item tool is also selected) | ||
clicking on a section of the cell, changes the location of the 'fixed' | ||
measurement/injection site (red dot). When :guilabel:`ShowPosition` is selected, | ||
clicking on a section will color both the section and the corresponding | ||
line in the results panel. | ||
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.. image:: ../../images/impedanx-logavsx.png | ||
:align: center |
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.. _impratio: | ||
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ImpedanceRatio | ||
-------------- | ||
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Tool for plotting voltage attenuation or impedance at a specific measurement and | ||
injection site as a function of log frequency from 0.1 to 1000 Hz. | ||
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The measurement site is selected by first selecting the :guilabel:`SelectMeasure` item | ||
of the :guilabel:`SelectLocation` menu and then selecting a location on the neuron | ||
in the middle panel. A red dot denotes the measurement location. | ||
The injection site is selected by via selection of the :guilabel:`SelectInject` menu item. | ||
Measurement and injection sites are indicated by red and blue dots respectively. | ||
The :guilabel:`SwapMeasure/Inject` menu item swaps the measurement and injection sites. | ||
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The :guilabel:`Plot` menu specifies whether to plot log attenuation (default), | ||
input impedance, transfer impedance, or ``V(measure)/V(inject)``. | ||
Input impedance is plotted with | ||
respect to the measurement site and the injection site is unused. | ||
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This tool uses the :class:`Impedance` | ||
class to calculate voltage attenuations. | ||
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