Loading Framework and Core based library at the same time

[kalpeshdlad]

Environment

• Pythonnet version: 3.0.3
• Python version: 3.9.5
• Operating System: Windows
• .NET Runtime: 5

I have few library/module created in .NETFramework which I am using in python by loading via pythonnet. This is working fine so far after loading with clr from module.

I have a requirement to upgrade all libraries to latest core base due to increased performance and improvements. At the same time I need to ensure backward compatibility. Given this scenario, I learned that I can load either .NETFramework on Core at a time in a python via pythonnet.

Due to this constraint, I am wandering is there any way I can load both Core and Framework based library at the same time from 64 bot based python.
In worst case I can consider doing a communication on RPC channel either on Core or Framework based library.
Please help me to resolve this problem. or is there any other alternative I can try.

Thanks in advance.