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Disentangle protein-protein interactions networks by using a list of driver genes as baits, separating the network in different levels, each one of them more relevant to the drivers.

Netcutter automatically creates a neo4j database with all the protein networks and serves a web application for users to explore the different levels by using docker.

Configuration file

netcutter needs a netengine config file in order to compute the graphs and build the database/website. In this configuration file one has to set the necessary parameters and options for build.py to work. The syntax goes as follows:

# Comment
parameter=value
another_parameter=another_value

The parameters are the following:

  • project_name
  • output
  • neo4j_memory
  • neo4j_address
  • biogrid_file
  • string_file
  • ppaxe_file
  • drivers_file
  • alias_file
  • web_address
  • content_templates
  • logo_img

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Disentangle protein-protein interaction networks using a list of genes as drivers.

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