Quarto is an open source STEM publishing system. Its origin is in the R statistics language. Quarto produces documents in multiple formats, including HTML and PDF. It is based on Markdown. Via MathJax it has good math support. It is a strong candidate for producing accessible outputs, particularly for blind users. This is a Quarto website.
The current intent is to focus on providing some examples of accessible LaTeX help, andto provide some cheat sheets for blind students taking math modules. In these specialist areas, feedback from users is really important to ensure accessibility and other user needs. This is particularly important at the early stages of development.