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CMU-SAFARI / GateSeeder

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GateSeeder is the first near-memory CPU-FPGA co-design for alleviating both the compute-bound and memory-bound bottlenecks in short and long-read mapping. GateSeeder outperforms Minimap2 by up to 40.3×, 4.8×, and 2.3× when mapping real ONT, HiFi, and Illumina reads, respectively.

bioinformatics fpga genomics indexing seeding hbm sequence-alignment read-mapping long-reads minimap2 minimizers short-reads genome-on-diet
  • Updated Oct 3, 2023
  • C
RawHash

CMU-SAFARI / RawHash

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RawHash is the first mechanism that can accurately and efficiently map raw nanopore signals to large reference genomes (e.g., a human reference genome) in real-time without using powerful computational resources (e.g., GPUs). Described by Firtina et al. (published at https://academic.oup.com/bioinformatics/article/39/Supplement_1/i297/7210440)

bioinformatics nanopore seeding segmentation event-detection genome-analysis hash-tables contamination read-mapping relative-abundances nanopore-sequencing nanopore-analysis-pipeline nanopore-reads nanopore-data nanopore-minion raw-signal rawhash raw-nanopore-signal-analysis
  • Updated Jun 17, 2024
  • C

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