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The following major changes have been included:
- Addition of a second aging replicate (Figure 4)
- Addition of a mature immune cell experiment (Figure 3)
- Substantial expansion of the human study (Figures 5 and 6), including
- many more donors (13 instead of 2)
- combination of EPI-clone with mitochondrial lineage tracing
- combination of EPI-clone with scRNA-seq readout