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v1.0.0 - Initial Release

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@Alebraco Alebraco released this 22 Jan 00:54
· 10 commits to main since this release
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phagepickr is a bioinformatics tool designed to create evolution-proof bacteriophage cocktails. By analyzing bacterial receptor profiles, it selects phage combinations that maximize host compatibility and minimize bacterial resistance.

Key Features

  • Targeted Design: Generates phage cocktails tailored for specific bacterial species (e.g., E. coli, K. pneumoniae).
  • Phage Discovery: Uses a nearest-neighbor algorithm to identify phage candidates from phenotypically similar bacteria.
  • Maximized Diversity: Identifies the most distant phages via alignment to target multiple receptors.
  • Automated Data Retrieval: Automatically fetches metadata via NCBI Entrez.
  • Built-in Datasets: Includes pre-processed bacterial receptor and phage-host data.

Installation

git clone https://github.com/Alebraco/phagepickr
cd phagepickr
conda env create
conda activate phagepickr