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Do not tick the android scope entry. Since 4.8 it hooks nothing, and it has been reported to stop Zygisk loading. Tick only the system_server entry — your manager calls it system or system_server. It is no longer in the Recommended list.
Running your own device-owner app (OwnDroid and friends)? Add it under Device-owner spoof exempt apps on the Categories tab, or it will be told it is not the owner of the device.
Reported by @MootComb.
Full changelog: https://github.com/Bouteillepleine/DuckDevicePolicy/blob/main/CHANGELOG.md