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VirtualIce v1.0.0

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@alexjnoble alexjnoble released this 10 Sep 15:10
· 56 commits to main since this release
7a7c5cb

First release of VirtualIce. Features:

  • Generates half-synthetic cryoEM micrographs and particles from buffer images and PDB IDs, EMDB IDs, or local files.
  • Creates coordinate files (.star, .mod, .coord), not including particles obscured by junk/substrate or too close to the edge.
  • Adds Poisson noise and dose-dependent damage to simulated frames and Gaussian noise to particles.
  • Applies the Contrast Transfer Function (CTF) to simulate microscope optics.
  • Control over overlapping particles and particle aggregation.
  • Outputs micrographs in MRC, PNG, and JPEG formats, and optionally cropped particles as MRCs.
  • Multi-core and GPU processing.
  • Extensive customization options including particle distribution, ice thickness, microscope parameters, and downsampling.