Additional InferCNV Examples

Additional InferCNV examples can be found as indicated below:

• Glioblastoma derived from: Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 2014 Jun 20;344(6190):1396-401

In the glioblastoma data set, GTEx brain samples were used as the background signal. For the others, normal single cells were used as background.

• Melanoma derived from: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science. 2016

• Oligodendroglioma derived from: Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma Nature, November 2016

Note, a small oligodendroglioma data set is included as the example data in the infercnv software.

• Pediatric midline gliomas derived from: Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science. 2018

See the corresponding run.R example scripts provided, and the expected output infercnv heatmaps provided as png files.