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Releases: codebase/gnomancer
Releases · codebase/gnomancer
Release list
v0.5.1
Audit release.
- MCP: the
mcppackage is now a core dependency, souvx gnomancer serveworks out of the box; registry icon fixed. - Report: smarter at-a-glance (carrier states and high-odds sites get their own lines; PharmCAT genes that could not be resolved are no longer reported as normal; HLA-B*57:01 surfaced), sticky contents with top links, deep links open collapsed sections, phone-friendly tables and chart, new methods and glossary sections, tidy drug-gene tables, no more "nan%".
- Pipeline: hemizygous X calls in males are no longer flagged as artifacts; protective sites are not counted as negatives; robust yhaplo install under uv-created venvs;
--namesvalidated in family mode. - Installer: correct Linux Python version check, Java 17 check, broken-venv repair, PATH instructions.
- Docs: NOTICE.md credits, concrete health-wording rules, Java 17 requirement stated everywhere.
gnomancer v0.5.0
- Family mode:
gnomancer family dad.zip mom.zip me.zip(and the MCP toolfamily). Shared DNA segments per pair via apriha/lineage with a relationship estimate, shared maternal/paternal lines, side-by-side panel genotypes, which parent each allele came from for parent-parent-child sets, and a Mendelian-consistency check. Synthetic family generator for testing. - Haplogroup guide pages on gnomancer.com, linked from the report's lineage cards
- Installer skips Pythons whose XML module is broken (Homebrew bottles on macOS 26.2) and can fall back to a uv-managed Python
gnomancer v0.4.2
- First run downloads the open-source tools and references automatically (CLI and the MCP
analyzetool), souvx gnomancer serveis a zero-step install for assistant users.--no-setupopts out. - SHA-256 pinning for downloaded tools; ClinVar verified against NCBI's MD5
- Homebrew tap:
brew install codebase/tap/gnomancer
gnomancer v0.4.1
- One-page pharmacogenomics card (
pgx-card.pdf/.html) for a pharmacist or prescriber: PharmCAT diplotypes and phenotypes, the drugs each gene matters for, clotting and abacavir single-site results, and a clear 'array-based, provisional' footer. Linked from the report. - Announcement drafts in docs/announcements.md
gnomancer v0.4.0
- Population frequencies on every panel row: how common your genotype is in each 1000 Genomes super-population (Hardy-Weinberg from Ensembl GRCh37 allele frequencies), shown for your ancestry group with all five on hover
gnomancer watch REPORT_DIR: ClinVar reclassification check. Keeps a snapshot of every ClinVar-classified allele you carry, downloads new ClinVar releases, rescans, and reports only what changed. Also an MCP tool (clinvar_watch).- Protective homozygotes now listed under Reassuring; realistic synthetic demo profile
- Discord community: https://discord.gg/aGjqzqErQH
gnomancer v0.3.2
Registry metadata: MCP server name com.gnomancer/gnomancer. Installer now uses the PyPI package.
gnomancer v0.3.1
First release on PyPI: pipx install gnomancer && gnomancer setup.
- Package data ships inside the wheel; downloaded tools live in ~/.gnomancer via
gnomancer setup - MCP server (
gnomancer serve), Claude skill, registry manifest - Trusted publishing from GitHub Actions
gnomancer v0.3.0
- MCP server:
gnomancer serve(stdio). Tools: analyze, summary, section, lookup, narrative_prompt, set_narrative, clinvar_findings, pharmacogenomics; resources for the get-your-data guide and the current report. Works with Claude Desktop, Claude Code, Cursor and any MCP client, entirely locally. - Registry manifest (server.json) and publishing notes (docs/mcp-registry.md)
- Claude skill and plugin manifest
- gnomancer.com: get-your-data and install guides, one-line installer
gnomancer v0.2.0
- Plain-language 'at a glance' digest and a narrative-summary slot (--summary, summary-prompt.md, or --ai via Claude)
- ClinVar scan of every typed site with plausibility scoring
- PharmCAT star-allele pharmacogenomics with drug context and per-gene coverage
- Yleaf second-opinion Y haplogroup on current trees; ezancestry population estimate
- Editorial pass: readable condition and population names, no placeholder readings
gnomancer v0.1.0
First public release.
- Parses AncestryDNA, 23andMe, MyHeritage, FamilyTreeDNA, LivingDNA and VCF exports (via snps), remaps to GRCh37
- Quality metrics, independent sex inference, runs of homozygosity
- Y haplogroup via yhaplo, with a second opinion from Yleaf on current YFull / FTDNA / ISOGG trees
- mtDNA haplogroup via Haplogrep3 against rCRS
- Curated 111-site marker panel (ancestry, traits, health, carrier, pharmacogenomics) with strand checking
- ClinVar scan of every typed site, with plausibility scoring for array artifacts
- PharmCAT star-allele pharmacogenomics with per-gene coverage
- Optional ezancestry population classification
- Self-contained HTML report (light/dark, print, search, health sections collapsed by default) plus Markdown, TSV and JSON
Everything runs locally; the only network traffic is downloading public tools and references.
Not medical advice: confirm anything that matters with a clinical-grade test.