Stratotemplate

Configuration template for stratocumulus & more

Recommended Usage

Set up your “GClouder”

Create a GCloud VM

• Log in to Google Cloud, go to the "console" (which is the main dashboard) & enter the Compute Instance Dashboard.
• From here, create a new VM that will be your virtual devbox to work from (it doesn't need to be beefy).
  • Make sure that, under "Identity and API Access", you select "Allow full access to all Cloud APIs."
• Add your SSH key to the instance (under Management, disk, networking, SSH keys > SSH Keys at the bottom).
• The gcloud command-line tool will generate and use SSH keys for you

And click to let the magic happen.

Setup The Host

To SSH into your machine you can use ssh username@instance-ip, instance-ip is found on the information page for your instance after it boots up.
You can also setup a Host in your ~/.ssh/config file.
Let's call it GClouder in the following.

Get to the GClouder:

ssh GClouder

Install a few more things:

sudo apt-get update
sudo apt-get install -y unzip build-essential git

The VM comes with gcloud installed but this deployment does not have full capabilities; we need to get a fresh one (Cf. also https://code.google.com/p/google-cloud-sdk/issues/detail?id=336):

curl https://sdk.cloud.google.com | bash

… saying Yes to everything … and then, you need to reload your .bashrc (just type bash).

For some reason the zone has to be configured again (replace us-east1-c with your favorite part of the world):

gcloud config set compute/zone us-east1-c

Create an SSH key-pair for for gcloud itself:

gcloud compute ssh $(hostname) ls

and accept the prompts (with an empty password).

Get The Configuration Template

We use Git, so that you the user can save their configuration:

git clone https://github.com/smondet/stratotemplate.git
cd stratotemplate

Get a Ketrew Server

This section creates a functional Ketrew server with Google-Container-Engine.

Edit the file configuration.env, make sure you're happy with the $PREFIX and $TOKEN values.

Get the script, and run it:

wget https://raw.githubusercontent.com/hammerlab/stratocumulus/master/tools/gcpketrew.sh -O gcpketrew.sh

. configuration.env
sh gcpketrew.sh up
# The first time this may prompt for a `[Y/n]` question.

When the command returns the deployment is partially ready, one needs to ask for the status a few times before the “External IP” is available:

sh gcpketrew.sh status

When it's ready, a little more configuration is required (is this command fails; wait and try again a minute or so later until it succeeds; the container engine may be slow at creating “pods”):

sh gcpketrew.sh configure+local

(Warning: the +local part will append a line to the ~/.ssh/authorized_keys file, use configure if you don't want that).

At any time the status command will give you the URL of the Ketrew server's WebUI.

Of course, you can save your changes to the stratotemplate repository like any other git repo.

When you want to take the server down (and delete everything related to it):

sh gcpketrew.sh down

Get a Stratocumulus Environment

We're going to use Docker to get a fully functional OCaml/Opam/Stratocumulus environment.

Get Docker:

sudo apt-get install -y docker.io

Get the image:

sudo docker pull smondet/stratocumulus

Make $PWD accessible by the container:

chmod -R a+rw .

Get in:

sudo  docker run -it  -v $PWD:/hostuff/ smondet/stratocumulus bash

Now you're in the right environment to submit stratocumulus deployment jobs.

cd /hostuff

Edit further configuration.env to set GCLOUD_HOST, CLUSTER_NODES … cf. comments in the file.

. configuration.env

Use the URL provided above by sh gcpketrew.sh status to create a Ketrew configuration:

ketrew init --conf ./ketrewdocker/ --just-client $(cat $KETREW_URL)

Create an NFS server with storage:

KETREW_CONFIG=./ketrewdocker/configuration.ml ocaml nfs_server.ml up submit

If you'd like this NFS pool mounted on the cluster you're about to create, you should edit your configuration.env to add it to the CLUSTER_NFS_MOUNT list; stratotemplate does not do this automatically for you. Storage is mounted at /nfs-pool and the witness file is .stratowitness on the newly created servers. You can find the NFS VM name through the GCloud instance list; it will be prefixed with the $PREFIX in your configuration.

Create a compute cluster:

KETREW_CONFIG=./ketrewdocker/configuration.ml ocaml cluster.ml up submit

The 2 above commands submit workflows to the Ketrew server, you can monitor them with the WebUI (see cat $KETREW_URL).

Replace up with down to take the deployments down ☺

Using your machine

Stratotemplate provides a basic biokepi_machine for easy Biokepi.Edsl.Machine.t creation. This you can #use in a script to get a machine, required for most for Biokepi workflows.

A few environment variables need to be set in order for it to work:

1. PREFIX set already in configuration.env
2. BIOKEPI_WORK_DIR
3. GATK_JAR_URL and MUTECT_JAR_URL URLs to GATK and MuTect (1) JARs; Biokepi can't automatically download these because of the restrictive licenses on them.