Skip to content

v0.3.0 Fantastic Frituur

Latest

Choose a tag to compare

@nvnieuwk nvnieuwk released this 15 Jan 12:29
5f3dbe1

Added

  1. Added the samplesheet to the pipeline output as OUTDIR/samplesheet.csv
  2. Added the --bedpe parameter. This makes the pipeline output BEDPE files alongside the VCF files.
  3. Added parallelization on SV type to the delly flow
  4. Added a --gtf parameter for annotation of gene and transcript overlap using gatk SVAnnotate.
  5. Added StrVCTVRE as a new annotation tool

Changes

  1. Updated the pipeline to be compatible with future nextflow updates
  2. Removed the max_cpus, max_memory and max_time parameter in favor of the new built-in resourceLimits
  3. Replaced nf-validation with nf-schema
  4. Updated to nf-core template v3.2.0
  5. Fixed language server errors
  6. Removed the old output publishing code and used the new workflow output definitions instead
  7. Bumped the minimal nextflow version to 25.10.0
  8. Changed the --annotations_filter parameter to a --filter parameter. This parameter takes an argument of bcftools filter to filter the resulting VCFs.
  9. Removed the --delly_sv_types parameter.
  10. Moved all wisecondorx and qdnaseq outputs to a separate directory in each sample output.
  11. Bumped all annotation modules to the latest versions
  12. Reworked the annotation structure to a per tool structure. Specify the annotations tools you want to run with --annotate_tools. This parameter takes a comma-separated list of tool names (options: vep, vcfanno, svannotate, strvctvre or all (=> all tools))
  13. Updated to nf-core template v3.5.1
  14. Removed AnnotSV from the pipeline
  15. Removed the small_variants field from the samplesheet. Small variant VCFs are no longer used in the pipeline

Fixed

  1. Fail the pipeline when the sex determination failed. This will now prompt the user to add the sex to the samplesheet so the pipeline doesn't do any wrong assumptions
  2. Fixed the Jasmine module output VCFs being empty when no variants have been merged. This file now contains the header of one of the input VCFs
  3. Fixed a map issue when the sex field is empty in the samplesheet