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Literature updated: 2026-11-10
- Screened all records again and extracted all findings again with GPT-6 Luna,
which replaces Gemini 3 Flash, using revised extraction instructions and
output schemas. - Updated the evidence base through November 10, 2026, representing 23,855
papers: 18,794 primary studies, 4,720 reviews, and 341 meta-analyses. - Added phencyclidine (PCP) to the compounds in scope, with its literature
searched from 1800 onward. - Increased the number of papers whose findings are read from the full text,
from 10,324 to 11,539. Every full text is checked to belong to the paper it
is used for, and a preprint's text is no longer used in place of the
published article. - Revised how findings are mapped to compounds and research-area concepts.
- Removed retracted papers from the graph and added notices to papers with an
expression of concern. - Kept authors who share a name apart, and matched OpenAlex profiles to ORCID
records when the name and coauthors agree. - Compute finding IDs from the finding's content, so they stay the same across
rebuilds; IDs from earlier releases change. - Reject unsupported REST query-body fields and MCP arguments instead of silently
ignoring them. Clients with extra fields must correct their requests. - Add subject/object ID filters to paper search for matching a compound–outcome
pair on the same relationship. - Bind pagination cursors to the operation and filters as well as the release.
Previously issued cursors must be discarded and pagination restarted. - Clarify agent guidance on relationship interpretation, OR/AND filtering,
incomplete author lists, and truncated relationship results.