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Sungsik Kevin Kong edited this page Jun 24, 2026 · 16 revisions

ISMB 2026 IP4: Generating Realistic Synthetic Biological Data Using Phylogenetics


Tutorial Information

When July 12, 2026 · 14:00 – 18:00
Where Jefferson West
Website https://www.iscb.org/ismb2026/whats-happening/tutorials#ip4

Instructors

Sungsik Kong🌿

Research Scientist
RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS)
Saitama, Japan

Max Hill🌺

Temporary Assistant Professor
Department of Mathematics, University of Hawai‘i at Mānoa
Hawai‘i, USA


Schedule

Time Activity
14:00 – 14:45 Introduction and Preliminaries
14:45 – 15:45 Hands-on Activity 1: Species Trees and Gene Trees
15:45 – 16:00 ☕ Coffee Break
16:00 – 16:30 Hands-on Activity 1: Species Trees and Gene Trees (Continued)
16:30 – 18:00 Hands-on Activity 2: DNA Sequence Simulation

About This Tutorial

Synthetic biological data are essential for benchmarking bioinformatics tools, evaluating phylogenetic methods, and developing machine learning models. In this tutorial, participants will learn how to simulate species trees, gene trees, and DNA sequence data using modern phylogenetic methods and software.

Topics include the Yule and birth-death models, the multispecies coalescent, and sequence evolution models ranging from JC69 to GTR. Through hands-on activities, participants will gain practical experience generating realistic datasets and understanding how evolutionary parameters shape biological data.


Intended Audience

This tutorial is intended for bioinformaticians, computational scientists, machine learning researchers, and students interested in biological data simulation. No strong biology background is required. Familiarity with the command line and R, Python, or Julia is recommended.

💻 Participants should bring a laptop with Internet access.

Happy simulating! 🌿


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