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Perian on OS X Yosemite #11
You will need to use the older QuickTime Player 7 in order to use Perian for playback, as QuickTime in Mavericks and later wants files to be readable by AVFoundation.
Also, more information for what you are trying to play, including codecs, would be appreciated.
There is currently no plans to expand Perian to extend the Mavericks and later version of QuickTime because there is no known way of expanding AVFoundation. If/when Apple makes it known that additional codecs can be added, then Perian will be able to be updated for more recent versions of OS X.
Note that there other players out there, like VLC, which can play a wide range of audio and video formats.
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