If a notification pops up it results in the content of the page to temporarily rearrange. The grid moves down under the mouse pointer where a user can incorrectly select the wrong button.
Notifications should be behaving as overlays or have a reserved space on the page.
Overlays work better because they don't use screen estate.
Make sure that if multiple notifications occur on a smaller screen that these notifications do not conflict with the rest of the page and the user is still able to use the UI.