simpleR: Designers and simulators of clinical trials based on SIMPLE.
simpleR is an R Software standing on the shoulders of SIMPLE, an R software for simulation of clinical trials in a modular manner. See Meyer et al. 2023 for more information about SIMPLE v0.2. simpleR uses SIMPLE v0.3, which includes one breaking change compared to v0.2, allowing for many more types of trials to be simulated.
In folder R of simpleR, there are two subfolders: Designers and Simulators. Folder Designers contains different types of designs, which are modifications/extensions of the base design provided by SIMPLE. Folder Simulators contains scripts used for simulation of those designs, which typically create results files in folder Output (at the same level as folder R), as well as other files, e.g., for postprocessing of the created results files to create summary datafiles or plots.
Currently included designers are
For master protocols of single-arm studies.
Currently included simulators are
Uses designer "Single-arm".