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Welcome to the BiERapp wiki!
BiERapp is an interactive web application for assisting in gene prioritization in whole exome sequencing (WES) experiments. BIERapp uploads standard VCF formats and provides different filtering options for the variants based on known population frequencies, predicted pathologic effect, consequence types, etc. Its most interesting feature is an intuitive filter that allows reproducing any familiar pedigree with any inheritance model (including incomplete penetrance) and facilitates the selection of variants (and genes with deleterious variants) segregating along the family. Also case-control or sporadic de novo mutational diseases can be analysed in this framework. BIERapp also manages efficiently missing values.
BierApp is a web-based
BierApp is implemented using
BierApp has been designed with these goals in mind:
- 100% web-based using open standards such as HTML5 and SVG. No plugins or other technologies such as Flash or Java Applets are needed
In the Tutorial you will learn how to use BierApp web application. Tutorial covers main functionality such as:
- creating an account
- user interface functionality
- ...