PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease

Supporting Information for the paper "PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease"

PINNet is a deep neural network (DNN) model with pathway prior knowledge from either the Gene Ontology or Kyoto Encyclopedia of Genes and Genomes databases.

Dataset

All gene expression data used in this paper are available and can be accessed here: GSE33000 and ADNI.

Get Started

1. Install requirements.txt to set up the envirnoment.
2. All default arguments for demo are provided in the dataPre.py.
3. Run the main.py to train and test the model.