Home

<iframe width="640" height="360" src="//www.youtube.com/embed/RSQrmiAYiN0" frameborder="0" allowfullscreen></iframe>

RETCAD is a software suite developed for the design and analysis of FRET networks. It is composed of the following modules:

## RETSim which is an engine for Förster Resonance Energy Transfer simulation. It supports several FRET simulaiton algorithms, some of which can capture saturation effects. ## Visualizer which is internally connected to RETSim and can visualize the simulation results in the form of charts. It can also perform user-defined post-simulation processing on the output of RETSim. ## RETLab which is a scripting engine designed specifically for FRET network design-space exploration. It can automatically initialize template networks based on a set of user-defined rules, and simulate each one with RETSim, and finally rank the results based on user-defined metrics. ## Dye Explorer which is a tool for inspecting dyes (fluorophore types). It has a database of more than 300 dyes with their photo-physical properties. It can sort any user-created list of dyes by absorption, or emission at a given wavelength or by the spectral overlap with a given dye as the donor- or acceptor. ## Spectrum Analyzer which is a search engine capable of executing sophisticated spectral or photo-physical queries. This tool is useful when the desired constraints span over multiple dyes and therefore manual search is cumbersome; for example searching among > 100 candidate dyes for three RET pairs with minimal direct excitation, maximal spectral overlap and minimum crosstalk.