Phylogenetic and statistical analyses of apoptotic gene repertoire evolution across Metazoa.
The analytical workflow that generated results and figures in the main text focused on genetic loci from the KEGG human apoptosis pathway can be reproduced by running the R Markdown script apoptosis-KEGGHomo.Rmd.
Further analyses on additional apoptosis markers presented in the supplementary material (GeneGlobe and the Drosophila KEGG pathway) can be reproduced using apoptosis-Global.Rmd.
All input files required by the workflows are available in the inputs/ directory.
Note: The initial execution of either workflow will begin with a time-consuming step (several minutes) to parse the OrthoFinder output and generate an R Object to the working directory that will be read into memory quickly during subsequent executions.