How to make exon/intron classification or genome annotation with evo2?

[hxtjc]

Hi, evo 2 is an amazing tools!

After reading the article(Genome modeling and design across all domains of life with Evo 2), I want to try to make a exon/intron classification or genome annotation with evo2. I've installed evo2, but I still don't know how to use it for exon/intron classification or genome annotation. I found the article 4.3.9 Exon/intron classification:

but I can't find "evo2_7b_gen".

I also red the notebook of "Zero-shot prediction of BRCA1 variant effects with Evo 2", but I didn't understand which step can be used to annotate a genome.

Can you give some tips and help?

[garykbrixi]

Hello, thanks for your question. "evo2_7b_gen" refers to Evo 2 7b base model (8k seq length)

The BRCA1 notebook example is for mutation effect prediction, not genome annotation. We have not yet released the exon/intron classification examples, but we do want to release this when it is ready