[nd2reader](https://github.com/Open-Science-Tools/nd2reader/issues/69) does not work with newer versions of Python/Numpy and it looks like it is not maintained any more. Until this is fixed you can use [ggirelli/radiantkit](https://github.com/ggirelli/radiantkit) or [nd2tool](https://github.com/elgw/nd2tool), besides Fiji etc. ## Suggestion Switch to [tlambert03/nd2](https://github.com/tlambert03/nd2)