AlphaFoldAnalysisEngine

Comprehensive AlphaFold2 structural prediction analysis engine for proteome-scale confidence scoring and disorder prediction.

Features

• Proteome-scale pLDDT confidence scoring and classification
• Predicted Aligned Error (PAE) matrix analysis for domain boundaries
• Intrinsically disordered region (IDR) prediction and characterization
• Structural ensemble generation and RMSD analysis
• High-confidence structural feature extraction and visualization

Results

500 proteins; Mean pLDDT=66.48; High conf=33.6%; Mean disorder=19.25%; Ensemble RMSD=2.44Å

Usage

pip install numpy scipy matplotlib
python alphafold_analysis_engine.py

Tags

alphafold2, plddt, predicted-aligned-error, structural-prediction, intrinsically-disordered-proteins