Spatial transcriptomics analysis engine for Visium data processing, tissue domain identification, spatially variable gene detection, and niche characterization.
- Visium spot-level gene expression processing and QC
- Spatial clustering and tissue domain identification
- Spatially variable gene detection using Moran's I statistic
- Cell type deconvolution and spatial mapping
- Tissue architecture and cellular niche characterization
3000 spots × 2000 genes; 5 domains; Top Moran's I=0.921; 1965 SV genes
pip install numpy scipy matplotlib
python spatial_transcriptomics_engine2.pyvisium, cell-type-mapping, spatial-clustering, tissue-architecture, niche