CRAM support added w/samtools. Multithreaded computation is added for…#66
Merged
valeu merged 1 commit intoBoevaLab:masterfrom Oct 14, 2019
Merged
CRAM support added w/samtools. Multithreaded computation is added for…#66valeu merged 1 commit intoBoevaLab:masterfrom
valeu merged 1 commit intoBoevaLab:masterfrom
Conversation
… samtools. CRAM for sambamba is disabled as there is a sambamba bug when reading CRAMs.
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
Several changes:
1- CRAM support is added when samtools is used. Sambamba is disabled for CRAM, since sambamba uses a very old version of htslib that causes segmentation fault with CRAM files.
2- Sambambathreads now defaults to maxThreads even when samtools is used. The value is passed to samtools for multithreaded decompression (-@ maxThreads).
3- fastaFile in BAF options is used for the reference genome for CRAM decompression.