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PRAD_EMSeq

PRAD_EMSeq is a code repository that contains necessary R scripts and processed files for EM-seq data interpretation and visualization.

File introduction

PRAD_EMSeq_interpretation.R is the main file of the pipeline. And machine_learning folder includes three R files corresponding to the three machine learning algorithms, Elastic Net Regression, XGBoost, and Logistic Regression, used in this project.

All_merged_DMRs_sig_methy_group_clinics_infor.csv is the main data of visualization. It has methylation percentages of all significant DMRs and clinical information of each patient. You can find it in the folder processed_data.

Relavant manuscript is under editor review in Biology Open.

(Waiting to be published~)

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