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Gens integration and visualization of all alignments of a case group

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@northwestwitch northwestwitch released this 04 Mar 10:04
0780a0b

[4.30]

Added

  • Introduced a reset dismiss variant verb
  • Button to reset all dismissed variants for a case
  • Add black border to Chromograph ideograms
  • Show ClinVar annotations on variantS page
  • Added integration with GENS, copy number visualization tool
  • Added a VUS label to the manual classification variant tags
  • Add additional information to SNV verification emails
  • Tooltips documenting manual annotations from default panels
  • Case groups now show bam files from all cases on align view

Fixed

  • Center initial igv view on variant start with SNV/indels
  • Don't set initial igv view to negative coordinates
  • Display of GQ for SV and STR
  • Parsing of AD and related info for STRs
  • LoqusDB field in institute settings accepts only existing Loqus instances
  • Fix DECIPHER link to work after DECIPHER migrated to GRCh38
  • Removed visibility window param from igv.js genes track
  • Updated HPO download URL
  • Patch HPO download test correctly
  • Reference size on STR hover not needed (also wrong)
  • Introduced genome build check (allowed values: 37, 38, "37", "38") on case load
  • Improve case searching by assignee full name
  • Populating the LoqusDB select in institute settings

Changed

  • Cancer variants table header (pop freq etc)
  • Only admin users can modify LoqusDB instance in Institute settings
  • Style of case synopsis, variants and case comments
  • Switched to igv.js 2.7.5
  • Do not choke if case is missing research variants when research requested
  • Improve create new gene panel form validation
  • Make XM- transcripts less visible if they don't overlap with transcript refseq_id in variant page
  • Color of gene panels and comments panels on cases and variant pages