Skip to content

Add propanotrophic chlorinated-ethene cometabolism community#73

Merged
realmarcin merged 2 commits into
mainfrom
claude/propanotrophic-tce-cdce-community
May 20, 2026
Merged

Add propanotrophic chlorinated-ethene cometabolism community#73
realmarcin merged 2 commits into
mainfrom
claude/propanotrophic-tce-cdce-community

Conversation

@realmarcin
Copy link
Copy Markdown
Contributor

Summary

Curate a new community YAML (`CommunityMech:000271`) from Faghihinezhad, Eshghdoostkhatami, Cupples 2026 Journal of Environmental Management, `doi:10.1016/j.jenvman.2026.129957` — "Characterization of multiple trichloroethene, cis-dichloroethene and 1,1-dichloroethene degrading propanotrophic communities".

System: propane-enriched aerobic mixed cultures derived from three KBS-LTER agricultural soils (T2, T3, T4) and an impacted-site sediment (West Coast Naval Station, Site 1), evaluated for cometabolic biodegradation of TCE, cDCE, and 1,1-DCE over successive transfers.

Members and roles

Taxon NCBITaxon Role Abundance
Rhodococcus opacus 37919 PRIMARY_DEGRADER DOMINANT (TCE)
Rhodococcus wratislaviensis 44752 PRIMARY_DEGRADER DOMINANT (TCE)
Mycolicibacterium 1866885 PRIMARY_DEGRADER DOMINANT (cDCE)
Mycobacterium 1763 PRIMARY_DEGRADER COMMON (cDCE)
Pseudonocardia 1847 PRIMARY_DEGRADER (PARTIAL) DOMINANT (1,1-DCE)
P. broussonetiae 2736640 PRIMARY_DEGRADER COMMON (Site 1 only)
Methylibium 316612 CROSS_FEEDER RARE
Burkholderiaceae 119060 CROSS_FEEDER RARE

Interactions

  1. Propane-cometabolic TCE degradation by Rhodococcus (CROSS_FEEDING via group-5 prmABCD)
  2. Propane-cometabolic cDCE degradation by Mycolicibacterium and Mycobacterium (CROSS_FEEDING; group-6 SDIMO with prmACDB ordering — PARTIAL since expression not examined)
  3. Substrate-specific selection across the three chlorinated ethenes (COMPETITION at COMMUNITY_LEVEL)
  4. 1,1-DCE-driven inhibition of propanotrophs (COMPETITION at COMMUNITY_LEVEL)

Plus four environmental factors: propane growth substrate, chlorinated-ethene concentrations, inoculum source, aerobic shaken incubation.

Storage

  • PDF: tracked at `references_pdfs/Faghihinezhad_2026_propanotrophic_TCE_cDCE_DCE.pdf` (new directory — no prior PDF storage convention in the repo)
  • Cache: `references_cache/DOI_10.1016_j.jenvman.2026.129957.md` carries the full text extracted from the PDF (`content_type: full_text`) so snippets can validate against methods/results passages that the abstract alone does not cover

Test plan

  • `just validate kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml` — no schema issues
  • `just validate-references kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml` — all snippets pass as substrings of the cached full text
  • `just validate-references-all` still reports 39 errors (no new errors)

🤖 Generated with Claude Code

Curate a new community YAML (CommunityMech:000271) from
Faghihinezhad, Eshghdoostkhatami, Cupples 2026 Journal of
Environmental Management,
doi:10.1016/j.jenvman.2026.129957,
"Characterization of multiple trichloroethene, cis-dichloroethene
and 1,1-dichloroethene degrading propanotrophic communities".

System: propane-enriched aerobic mixed cultures derived from three
KBS-LTER agricultural soils (T2, T3, T4) and an impacted-site
sediment (West Coast Naval Station, Site 1), evaluated for
cometabolic biodegradation of TCE, cDCE, and 1,1-DCE over
successive transfers.

Members and roles:
- Rhodococcus opacus and R. wratislaviensis (PRIMARY_DEGRADER,
  DOMINANT in TCE-amended enrichments)
- Mycolicibacterium and Mycobacterium (PRIMARY_DEGRADER, dominant
  in cDCE-amended enrichments)
- Pseudonocardia (PRIMARY_DEGRADER, dominant in 1,1-DCE-degrading
  cultures; carries truncated prmA so transformation enzyme
  unclear - PARTIAL)
- Pseudonocardia broussonetiae (Site-1-specific MAG)
- Methylibium and an unclassified Burkholderiaceae (CROSS_FEEDER,
  RARE non-actinobacterial propane-monooxygenase MAGs from
  cDCE enrichments)

Interactions captured:
- Propane-cometabolic TCE degradation by Rhodococcus (CROSS_FEEDING
  via group-5 prmABCD)
- Propane-cometabolic cDCE degradation by Mycolicibacterium and
  Mycobacterium (CROSS_FEEDING via group-6 SDIMO with prmACDB
  ordering - PARTIAL since expression not examined)
- Substrate-specific selection across the three chlorinated ethenes
  (COMPETITION at COMMUNITY_LEVEL)
- 1,1-DCE-driven inhibition of propanotrophs (COMPETITION at
  COMMUNITY_LEVEL)

Plus four environmental factors: propane growth substrate,
chlorinated-ethene concentration ranges, inoculum source, aerobic
shaken incubation.

Storage:
- Full-text PDF tracked at references_pdfs/Faghihinezhad_2026_propanotrophic_TCE_cDCE_DCE.pdf
  (new directory; no prior PDF storage convention in the repo).
- references_cache/DOI_10.1016_j.jenvman.2026.129957.md now carries
  the full-text extracted from the PDF (content_type: full_text),
  enabling snippet validation against methods/results passages that
  the abstract alone does not cover.

All snippets validate as substrings of the cached full text;
`just validate-references-all` reports 39 errors (unchanged from
main - the new community adds zero).

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>
Copilot AI review requested due to automatic review settings May 20, 2026 00:20
Copy link
Copy Markdown

Copilot AI left a comment

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Pull request overview

Adds a new curated CommunityMech community record (CommunityMech:000271) describing propane-enriched, aerobic propanotrophic mixed cultures capable of cometabolic degradation of TCE, cDCE, and (in subsets) 1,1-DCE, backed by a cached full-text reference for DOI:10.1016/j.jenvman.2026.129957.

Changes:

  • Adds a new community YAML capturing members/roles, ecological interactions, and environmental factors for the propanotrophic chlorinated-ethene cometabolism enrichments.
  • Adds a new references_cache full-text markdown file for the cited 2026 J. Environmental Management article to support evidence snippets.

Reviewed changes

Copilot reviewed 1 out of 3 changed files in this pull request and generated 6 comments.

File Description
kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml New curated community definition (members, interactions, environmental factors, evidence).
references_cache/DOI_10.1016_j.jenvman.2026.129957.md New cached full-text reference backing snippet validation for the community curation.
Comments suppressed due to low confidence (2)

kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml:321

  • This second trichloroethene entry also uses CHEBI:18045; the repo convention elsewhere is CHEBI:16602 for trichloroethene. Please update this term for consistency across curated communities.
  - preferred_term: trichloroethene
    term:
      id: CHEBI:18045
      label: trichloroethene

kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml:271

  • This interaction description states that Mycolicibacterium and Mycobacterium both carry propane monooxygenase operons driving cDCE oxidation. The cached text explicitly reports prm operon-containing MAGs as Mycobacterium (and others), but does not indicate Mycolicibacterium MAGs/operons. Please adjust the wording (e.g., describe Mycolicibacterium as dominant by read-based taxonomy without asserting operon carriage) or add evidence that directly supports operon presence in Mycolicibacterium.
- name: Propane-Cometabolic cDCE Degradation by Mycolicibacterium and Mycobacterium
  description: Mycolicibacterium dominates and Mycobacterium follows in all
    four cDCE-amended enrichments; both genera carry propane monooxygenase
    operons (with prmACDB ordering for the Mycobacterium MAGs, suggestive of
    group-6 SDIMOs) that drive cometabolic cDCE oxidation while propane is
    the growth substrate.

💡 Add Copilot custom instructions for smarter, more guided reviews. Learn how to get started.

Comment thread references_cache/DOI_10.1016_j.jenvman.2026.129957.md Outdated
Comment thread references_cache/DOI_10.1016_j.jenvman.2026.129957.md Outdated
Comment thread kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml Outdated
Comment thread kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml Outdated
Comment thread kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml Outdated
Comment thread kb/communities/Propanotrophic_Chlorinated_Ethene_Cometabolism_Enrichment.yaml Outdated
Six review points from Copilot:

- Cache cleanup: re-extract the PDF text with control-byte removal
  and paragraph-aware wrapping. The previous version of the cache
  contained 6 NUL bytes + 6 other ASCII control bytes (which could
  flip the file to binary in some tools) and was stored as a single
  ~109 kB line. Now: 0 NUL/control bytes, sentence-respecting
  paragraph layout wrapped at 100 columns, same content, all
  snippets still validate.
- CHEBI ID for trichloroethene: 18045 -> 16602 to match the repo-
  standard term used by 4 other chlorinated-ethene communities
  (Dehalococcoides Syntrophomonas / Pelobacter / Desulfovibrio
  cocultures and KB1).
- Mycolicibacterium notes: drop the unsourced claim that this genus
  carries prmACDB-ordered group-6 SDIMO operons. The paper's
  MAG-level results report propane monooxygenase operons on
  Rhodococcus, Mycobacterium, and Pseudonocardia MAGs, plus two
  Proteobacterial MAGs; the prmACDB ordering is specifically
  attributed to Mycobacterium. Updated notes flag that
  Mycolicibacterium dominance is from community-composition
  analysis, not MAG-level prm operons.
- TCE-cometabolism description softened: the previous wording
  "the group-5 propane monooxygenase (prmABCD) is implicated as
  the enzyme that fortuitously oxidizes TCE" is stronger than the
  abstract supports (functional gene analysis identified the
  operons but expression was not examined). Now: states that
  Rhodococcus MAGs carry the prmABCD operon and that both group 5
  and putative group 6 monooxygenases were identified in the
  community, with the caveat that expression was not examined and
  the in-vivo TCE-oxidizing enzyme is not directly demonstrated.
- 1,1-DCE-inhibition description softened: drop the unsupported
  "rather than its irreversible transformation products" assertion.
  The evidence supports inhibitory/toxic effects at elevated
  concentrations but does not distinguish parent compound vs.
  transformation products; description now reflects that limitation
  explicitly.

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>
@realmarcin realmarcin merged commit a56e39b into main May 20, 2026
@realmarcin realmarcin deleted the claude/propanotrophic-tce-cdce-community branch May 20, 2026 00:38
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

2 participants