v0.0.1
🚀 CellColoc v0.0.1
June 21, 2026
First public main release of CellColoc.
This initial release provides:
- the reusable
cellcolocPython package for interactive, segmentation-based colocalization analysis in microscopy images - stepwise user-script workflows for VS Code interactive window and notebook-like execution
- OMIO-based microscopy loading with
TZCYXhandling - automatic 2D versus 3D detection from the raw z dimension
- voxel-size resolution from explicit user input or OMIO metadata, with fallback to
(1.0, 1.0, 1.0)when necessary - channel-wise segmentation method selection with support for:
cellposeotsulipercentile
- optional ROI drawing in napari
- optional whole-image analysis as one single ROI
- optional reuse of previously saved ROI masks
- per-cell overlap analysis and marker-positivity classification
- standardized detailed, summary, and overview result tables
- standardized export into a
results/subfolder next to the raw dataset - occupancy metrics for every segmented channel
- optional third-channel segmentation and occupancy quantification
- optional third-channel cell-positivity analysis and double-positive reporting
- optional global z cropping for internal analysis
- optional global z projection using:
maxmeanmedianstdvar
- optional anisotropy handling for true 3D Cellpose runs
- optional
flow3d_smoothsupport for Cellpose - optional image prefiltering with:
gaussianmedianlaplacian_of_gaussian- ordered prefilter chains
- optional label postfiltering with:
min_intensitylocal_contrastbright_pixel_support- ordered postfilter chains
- fast Cellpose cache-based refinement using stored network outputs
- optional manual napari mask editing followed by table recomputation
- reusable visualization helpers with selective layer refreshing in napari
- runtime fallback handling for cache and config directories when desktop libraries cannot write to default locations
- packaging metadata for installation via
pip
Packaging notes:
- PyPI package name:
cellcoloc - import name:
cellcoloc - optional interactive extra:
cellcoloc[interactive] - optional tested Cellpose 3 extra:
cellcoloc[cellpose3]