Markov Chain Model for analyzing the VesicleVoyager platform - a system for in vivo selection of surface displayed proteins that direct extracellular vesicles to tissue-specific targets.
This module implements a Markov model that captures the stochastic relationship between surface-displayed monobodies and their packaged DNA within extracellular vesicles (EVs).
Please see individual Branches within this repo for data associated with in vitro and in vivo experimental data.
Authors: Yuki Kawai-Harada, Mehrsa Mardikoraem, Ashley V. Makela, Katherine Lauro, Jeannie Lam, Christopher H. Contag, Daniel Woldring, Masako Harada Affiliation: Institute for Quantitative Health Science and Engineering, Michigan State University