Meta-Analysis

This repository contains the code files for the paper: Evaluating the potential of acupuncture for Alzheimer’s disease treatment: A meta-analysis and systematic review of mouse model studies

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Requirements

Software

• R (version ≥ 4.0.0)
• RStudio

R Libraries

Before running the .Rmd file, ensure you have the following libraries installed:

install.packages(c("meta", "metafor", "metasens", "dplyr", "readxl", "ggplot2", "netmeta", "igraph", "dmetar", "Cairo"))

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How to Use

Set Up the Data Directory

The RMarkdown files for each outcome variable relies on data_dir variable. Set the data_dir path to be:

Notes and data for listed articles

which is provided in the repo.

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Outputs

Meta-Analysis Outputs

• Forest Plot: Visualizes meta-analysis results.
• Funnel Plot: Identifies potential publication bias.
• Bias Assessment: Performed using the metabias and trimfill functions.

Network Meta-Analysis Outputs

• Network Graph: Visualizes the relationships between treatment and control groups.
• Network Forest Plot: Summarizes the results of the network meta-analysis.

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